{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:24:35Z","timestamp":1763036675179},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,2,2]],"date-time":"2012-02-02T00:00:00Z","timestamp":1328140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hyalinizing clear cell adenocarcinoma (HCCA) is a rare salivary gland malignancy. To our knowledge, there are no published reports of primary clear cell carcinoma of the vallecula.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 59\u2010year\u2010old man with progressive dysphagia and otalgia underwent direct laryngoscopy with biopsy of a vallecular mass. The pathology results returned as clear cell adenocarcinoma. He underwent a wide local excision for his T<jats:sub>2<\/jats:sub>N<jats:sub>0<\/jats:sub>M<jats:sub>0<\/jats:sub> stage II tumor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clear cell adenocarcinoma of the oropharynx typically presents as a painless neck mass and it can be difficult to distinguish from other clear cell malignancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Immunohistochemical staining is essential for narrowing the differential diagnosis of these lesions. Treatment is controversial but usually consists of wide local excision and possibly a neck dissection. \u00a9 2012 Wiley Periodicals, Inc. Head Neck, 2012<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.22940","type":"journal-article","created":{"date-parts":[[2012,2,2]],"date-time":"2012-02-02T11:20:35Z","timestamp":1328181635000},"source":"Crossref","is-referenced-by-count":8,"title":["Hyalinizing clear cell adenocarcinoma of the oropharynx"],"prefix":"10.1002","volume":"35","author":[{"given":"Eelam","family":"Adil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhave","family":"Setabutr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kael","family":"Mikesell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,2,2]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199401000-00007"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1258\/00222150260293718"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/014556131109000512"},{"key":"e_1_2_4_5_2","first-page":"127","article-title":"Clear cell carcinoma of the base of the tongue: MR imaging findings","volume":"28","author":"Uzochukwu NO","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310016929"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.104"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-008-0052-7"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.12.006"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23974"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.22940","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.22940","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T16:45:03Z","timestamp":1700671503000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.22940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,2]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1002\/hed.22940"],"URL":"https:\/\/doi.org\/10.1002\/hed.22940","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,2]]}}}