{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T06:52:05Z","timestamp":1760597525646},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,2,2]],"date-time":"2012-02-02T00:00:00Z","timestamp":1328140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We analyzed tissue incorporation, immune response, and neovascularization of AlloDerm and DermaMatrix in a rat model of postparotidectomy reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 8 male Sprague\u2013Dawley rats, 3\u2010dimensionally folded AlloDerm implants were placed in the left postparotidectomy bed and 3 in the anterior dorsum as controls. The same was done for DermaMatrix on the right side and posterior dorsum. Two animals were euthanized at 4, 8, and 12 days. A blinded pathologist assessed the degree of fibroblast proliferation, neovascularization, and inflammation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>When compared with the dorsum, DermaMatrix implants in the parotid bed had significantly higher numbers of inflammatory cells at 8 and 12 days (<jats:italic>p<\/jats:italic> = .049 and .0046). AlloDerm acted more consistently between the postparotidectomy bed and dorsum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>AlloDerm reacts similarly when comparing the postparotidectomy bed to the dorsum. DermaMatrix induces a more marked inflammatory reaction in the postparotidectomy bed when compared with the dorsum. \u00a9 2012 Wiley Periodicals, Inc. Head Neck, 2013<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.22952","type":"journal-article","created":{"date-parts":[[2012,2,2]],"date-time":"2012-02-02T11:19:27Z","timestamp":1328181567000},"page":"242-249","source":"Crossref","is-referenced-by-count":7,"title":["AlloDerm and DermaMatrix implants for parotidectomy reconstruction: A histologic study in the rat model"],"prefix":"10.1002","volume":"35","author":[{"given":"Sanjay M.","family":"Athavale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeet","family":"Rangarajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latif","family":"Dharamsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Wentz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore","family":"McRackan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendell G.","family":"Yarbrough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,2,2]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"174","article-title":"Treatment of complications of parotid gland surgery","volume":"25","author":"Marchese\u2010Ragona R","year":"2005","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199711000-00013"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.5.1.109"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200111000-00024"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/014556130708600820"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.125.8.833"},{"key":"e_1_2_6_8_2","unstructured":"LifeCell Corporation. 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