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Kaplan\u2013Meier estimates, log\u2010rank test, and Cox regression models were used for statistical analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred fifty\u2010nine patients were managed with surgery; 67 patients (25%) received adjuvant radiotherapy. Mean follow\u2010up was 60 months. The 5\u2010year local and regional control rates were 78% and 69.4%, respectively. The 5\u2010year overall, disease\u2010specific, and recurrence\u2010free survival rates were 69%, 70.9%, and 53%, respectively. The only significant predictor of both overall survival (OS) and disease\u2010free survival (DFS) on multivariable analysis was pathologic N classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Treatment of early tongue SCC effectively achieves local control and DFS. Nodal disease remains to be 1 of the most important prognostic factors in terms of recurrence and survival. \u00a9 2012 Wiley Periodicals, Inc. 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