{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T23:06:00Z","timestamp":1780700760120,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T00:00:00Z","timestamp":1337040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Head and neck cancer is a common second cancer in patients with a history of hematological malignancies. The purpose of this study was present the clinical characteristics and treatment outcomes of this group of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was conducted of all patients who had a history of hematological malignancy and developed head and neck cancer in a 10\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cohort had 10 patients; median age was 45.8 years. Most patients were nonsmokers and nondrinkers. Seven patients had chronic graft\u2010versus\u2010host disease. The median interval between the completion of treatment of hematological malignancy and the development of head and neck cancers was 8.79 years (range, 2.33\u201326.83 years). Six patients were alive and disease\u2010free, 3 developed local recurrence, and 3 had metachronous head and neck cancers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The risk factors and etiology of head and neck cancers in patients with hematological malignancy may be different from the ordinary population. \u00a9 2012 Wiley Periodicals, Inc. Head Neck, 2013<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23026","type":"journal-article","created":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T05:51:50Z","timestamp":1337061110000},"page":"729-732","source":"Crossref","is-referenced-by-count":9,"title":["Secondary head and neck cancer in patients with history of hematological malignancy"],"prefix":"10.1002","volume":"35","author":[{"given":"Joseph Chun\u2013Kit","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond King\u2013Yin","family":"Tsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Shing\u2013Howe","family":"To","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambrose Chung\u2013Wai","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmy Yu\u2013Wai","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai\u2013Kuen","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Ignace","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199703273361301"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1994.12.10.2187"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190290033341"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900201)65:3<473::AID-CNCR2820650316>3.0.CO;2-V"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705020"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704706"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(18)30249-1"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702339"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20160"},{"key":"e_1_2_6_11_2","unstructured":"Hong Kong Cancer Registry 2008 Annual Statistical Report. Hong Kong: Hospital Authority;2008."},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190127510"},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1128\/jcm.31.1.53-56.1993","article-title":"Detection of Epstein\u2013Barr virus and human papillomavirus in head and neck tumors","volume":"31","author":"Tyan YS","year":"1993","journal-title":"J Clin Microbiol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2004.06.003"},{"issue":"2","key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1288\/00005537-199002000-00016","article-title":"Squamous carcinoma of the head and neck in organ transplant recipients: possible role of oncogenic viruses","volume":"100","author":"Bradford CR","year":"1990","journal-title":"Laryngoscope"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2002.310302.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0215(20000715)87:2<228::AID-IJC12>3.0.CO;2-T"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.10.1115"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2004.00225.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20931"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-04-1152"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.3109\/13547501003797664"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2005.02.001"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2011.77"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2006.01264.x"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature01322"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e3283374ccf"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23026","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T17:16:18Z","timestamp":1700673378000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,15]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1002\/hed.23026"],"URL":"https:\/\/doi.org\/10.1002\/hed.23026","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,15]]}}}