{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:05:01Z","timestamp":1782252301991,"version":"3.54.5"},"reference-count":11,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T00:00:00Z","timestamp":1349827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Immunoglobulin G4 (IgG4)\u2013related sclerosing disease is a systemic disease characterized by extensive IgG4\u2010positive plasma cells and T\u2010lymphocyte infiltration of various organs. We present a case of a 69\u2010year\u2010old man with maxillary sinus IgG4 sclerosing disease, with orbital invasion treated with rituximab and dexamethasone pulse therapy. Surgery was used as well to debulk the disease and to obtain tissue for diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A PubMed search using the key phrase \u201cIgG4\u2010related Sclerosing Disease\u201d was performed. There were 304 different articles regarding the disease for a multitude of different organ sites. Of the 304 articles, there were 3 articles that reported this disease in the paranasal sinuses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IgG4\u2010related sclerosing disease is a rare entity in the head and neck. There are documented reports of steroid therapy for this disease, but the patient presented here demonstrated clinical progression of disease with steroids alone. The use of combination therapy of surgery, dexamethasone, and rituximab provided clinical improvement and stable disease determined by radiographic means. \u00a9 2012 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 35: E321\u2013E324, 2013<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23175","type":"journal-article","created":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T09:28:54Z","timestamp":1349861334000},"source":"Crossref","is-referenced-by-count":27,"title":["Immunoglobulin G4\u2013related sclerosing disease of the paranasal sinus"],"prefix":"10.1002","volume":"35","author":[{"given":"Robert H.","family":"Lindau","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Oregon Health and Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yungpo Bernard","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Methodist Hospital Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Allergy\/Immunology Methodist Hospital Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell B.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Nebraska Medical Center Omaha Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.3948"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.09.019"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2009.02425.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.07.073"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27435"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32834ddb4a"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-010-8214-2"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.01.034"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-06-229112"},{"key":"e_1_2_4_11_1","first-page":"2129","article-title":"Tumor necrosis factor inhibition in the treatment of refractory sarcoidosis: slaying the dragon?","volume":"34","author":"Sweiss N","year":"2007","journal-title":"J Rheumatol"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2009.03.010"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23175","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T18:15:29Z","timestamp":1696356929000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,10]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1002\/hed.23175"],"URL":"https:\/\/doi.org\/10.1002\/hed.23175","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,10]]}}}