{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:46:01Z","timestamp":1783392361411,"version":"3.54.6"},"reference-count":39,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,3,9]],"date-time":"2013-03-09T00:00:00Z","timestamp":1362787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>We compared clinical outcomes between patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesion and properly diagnosed as malignant lesion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The outcomes were compared between patients with benign lesion and malignant lesion (44 each) on preoperative fine\u2010needle aspiration cytology diagnosis who underwent conservative or radical surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five\u2010year lesion\u2010free survival (DFS) rates were 86.8% for benign lesion and 76.3% for malignant lesion (<jats:italic>p<\/jats:italic> = .128). Surgical extent did not significantly affect locoregional recurrence and DFS (<jats:italic>p<\/jats:italic> = .360). Univariate analysis showed that sublingual gland tumor, positive resection margin, and extraparenchymal extension (EPE) were significantly associated with DFS (<jats:italic>p<\/jats:italic> &lt; .05 each). On multivariate analysis, EPE remained an independent variable (<jats:italic>p<\/jats:italic> = .047, hazard ratio = 6.621, 95% confidence interval = 1.393\u201331.474).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The clinical outcomes of patients with salivary gland carcinomas misdiagnosed as benign are relatively favorable. Conservative surgery may be sufficient for patients with low\u2010grade and T1\u20132 salivary gland carcinomas. \u00a9 2013 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 35: 1764\u20131770, 2013<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23228","type":"journal-article","created":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T22:32:18Z","timestamp":1363127538000},"page":"1764-1770","source":"Crossref","is-referenced-by-count":11,"title":["Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions"],"prefix":"10.1002","volume":"35","author":[{"given":"In Sun","family":"Ryu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Lyel","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Ja","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pathology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010wook","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon Yuhl","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Yoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"},{"name":"Biomedical Research Institute Korea Institute of Science and Technology Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(99)70323-2"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080309"},{"key":"e_1_2_5_4_1","volume-title":"World Health Organization classification of tumours. 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