{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:09:48Z","timestamp":1791216588366,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There is much controversy regarding the effect of radiotherapy on facial nerve regeneration. However, the effect of brachytherapy has not been studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010three patients underwent total parotidectomy of which 13 were radical with immediate facial nerve repair with sural nerve grafts. Six patients (group 1) did not receive adjuvant treatment whereas 7 patients (group 2) received postoperative brachytherapy plus radiotherapy. Functional outcomes were compared using Facial Clima.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean percentage of blink recovery was 92.6 \u00b1 4.2 for group 1 and 90.7 \u00b1 5.2 for group 2 (<jats:italic>p<\/jats:italic> = .37). Mean percentage of commissural excursion restoration was 78.1 \u00b1 3.5 for group 1 and 74.9 \u00b1 5.9 for group 2 (<jats:italic>p<\/jats:italic> = .17). Mean time from surgery to first movement was 5.7 \u00b1 0.9 months for group 1 and 6.3 \u00b1 0.5 months for group 2 (<jats:italic>p<\/jats:italic> = .15).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Brachytherapy plus radiotherapy does not affect the functional outcomes of immediate facial nerve repair with nerve grafts. \u00a9 2013 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>36<\/jats:bold>: 113\u2013119, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23276","type":"journal-article","created":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T07:10:33Z","timestamp":1370070633000},"page":"113-119","source":"Crossref","is-referenced-by-count":37,"title":["Effect of postoperative brachytherapy and external beam radiotherapy on functional outcomes of immediate facial nerve repair after radical parotidectomy"],"prefix":"10.1002","volume":"36","author":[{"given":"Bernardo","family":"Hontanilla","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Cl\u00ednica Universidad de Navarra Navarra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan\u2010Shan","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Cl\u00ednica Universidad de Navarra Navarra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Marr\u00e9","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Cl\u00ednica Universidad de Navarra Navarra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0351-8"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160909500406"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-008-0859-y"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2009.01.005"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22357"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2012.02.003"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2008.10.009"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02852.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2007.03.037"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1961.00740020330013"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000275034"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946307200313"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197703000-00015"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1979.00790200003001"},{"key":"e_1_2_5_16_1","first-page":"112","article-title":"Facial nerve grafts: effects of postoperative irradiation","volume":"16","author":"Gullane PJ","year":"1987","journal-title":"J Otolaryngol"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00721-5"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21048"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00717-7"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22648"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2007.08.009"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300202"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23276","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T02:38:22Z","timestamp":1696387102000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1002\/hed.23276"],"URL":"https:\/\/doi.org\/10.1002\/hed.23276","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}