{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T20:35:23Z","timestamp":1789590923208,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T00:00:00Z","timestamp":1371168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Basaloid squamous cell carcinoma (BSCC) is a rare subtype squamous cell carcinoma (SCC) that frequently occurs in the larynx. BSCC is generally considered an aggressive SCC variant; however, because of its rarity, most studies are underpowered to detect statistical differences in disease\u2010specific survival (DSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the Surveillance, Epidemiology, and End Results (SEER) database, we compared clinicopathologic data and DSS between patients with laryngeal BSCC and SCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with relative SCC, those with laryngeal BSCC, presented with more advanced local, regional, and distant disease (<jats:italic>p<\/jats:italic> &lt; .001). Patients with BSCC had worse DSS, regardless of stage, tumor location within the larynx (glottis\/supraglottis; <jats:italic>p<\/jats:italic> &lt; .001), or treatment received (<jats:italic>p<\/jats:italic> \u2264 .052).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Analysis of the largest laryngeal BSCC series to date (<jats:italic>n<\/jats:italic> = 145) demonstrates that BSCC carries a worse prognosis than conventional SCC of the larynx. \u00a9 2013 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 36: 164\u2013170, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23286","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T08:28:14Z","timestamp":1371198494000},"page":"164-170","source":"Crossref","is-referenced-by-count":36,"title":["Basaloid squamous cell carcinoma of the larynx: Analysis of 145 cases with comparison to conventional squamous cell carcinoma"],"prefix":"10.1002","volume":"36","author":[{"given":"Valerie A.","family":"Fritsch","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Hollings Cancer Center Medical University of South Carolina Charleston South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Lentsch","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Hollings Cancer Center Medical University of South Carolina Charleston South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,14]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Pathology and genetics. 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