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Eight cases were N+. Twenty\u2010one patients were treated with surgery plus brachytherapy because of close\/positive margins. Nine fractions of 5 Gy were given over 5 days in 67% of the patients. Elective neck treatment was performed in 23 cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 10\u2010year actuarial local control was 94.6%, nodal regional control was 88.6%, disease\u2010free survival was 84.6%, and cause\u2010specific survival was 93.2%. In the univariate analysis, T4 tumors had higher risk of local failure and T2 of regional relapse. In the multivariate analysis, skin involvement was the only significant factor for tumor progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>HDR\u2010brachytherapy yields excellent local control rates. Skin involvement increases the risk of local and cervical recurrence. Elective neck treatment should be done in T2 to T4 tumors or with skin or commissure involvement. \u00a9 2014 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 36: 1737\u20131742, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23529","type":"journal-article","created":{"date-parts":[[2013,10,25]],"date-time":"2013-10-25T13:48:34Z","timestamp":1382708914000},"page":"1737-1742","source":"Crossref","is-referenced-by-count":27,"title":["Prognostic factors in squamous cell lip carcinoma treated with high\u2010dose\u2010rate brachytherapy"],"prefix":"10.1002","volume":"36","author":[{"given":"Jose\u2010Luis","family":"Guinot","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Fundacion Instituto Valenciano de Oncologia (I.V.O.) 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