{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T01:40:01Z","timestamp":1793324401535,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T00:00:00Z","timestamp":1395273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010101","name":"Taichung Veterans General Hospital","doi-asserted-by":"crossref","award":["TCVGH 1027003C"],"award-info":[{"award-number":["TCVGH 1027003C"]}],"id":[{"id":"10.13039\/501100010101","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to investigate factors associated with carotid blowout in the cervical portion of patients with head and neck cancer in a large cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed patients with head and neck cancer and identified those with carotid blowout. Variables of patients with and without carotid blowout were compared and associated factors were investigated by logistic regression model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 2590 patients were included in the final analysis and 102 patients (3.9%) developed carotid blowout in the cervical region. Body mass index (BMI) &lt;22.5 kg\/M<jats:sup>2<\/jats:sup>, primary site in the hypopharynx or oropharynx, open wound in the neck requiring wet dressing, radical neck dissection, and total radiation dose to the neck \u226570 Gy were independent factors associated with carotid blowout.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>After completion of treatment in patients with head and neck cancer, carotid blowout was an uncommon complication with catastrophic results. Recognition of associated factors helps physicians to identify those at risk. \u00a9 2014 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>37<\/jats:bold>: 265\u2010272, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23590","type":"journal-article","created":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T16:16:49Z","timestamp":1387901809000},"page":"265-272","source":"Crossref","is-referenced-by-count":113,"title":["Carotid blowout in patients with head and neck cancer: Associated factors and treatment outcomes"],"prefix":"10.1002","volume":"37","author":[{"given":"Yi\u2010Juin","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen\u2010Chi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong\u2010San","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Ching","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Taichung Veterans General Hospital Taichung Taiwan Republic of China"},{"name":"Faculty of Medicine School of Medicine, National Yang\u2010Ming University Taipei Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010An","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan Republic of China"},{"name":"Faculty of Medicine School of Medicine, National Yang\u2010Ming University Taipei Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2010.08.029"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2011.06.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(79)90429-X"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197307000-00006"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510011000X"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.09.056"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-004-0775-3"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00007526"},{"key":"e_1_2_7_10_1","first-page":"843","article-title":"Endovascular therapy for the carotid blowout syndrome in head and neck surgical patients: diagnostic and managerial considerations","volume":"17","author":"Chaloupka JC","year":"1996","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2007.11.003"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200404000-00010"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941011900709"},{"key":"e_1_2_7_14_1","first-page":"306","article-title":"Radiation\u2010induced arterial injuries","volume":"93","author":"McCready RA","year":"1983","journal-title":"Surgery"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(73)80051-0"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197509)36:3<904::AID-CNCR2820360311>3.0.CO;2-U"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyt043"}],"container-title":["Head &amp; 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