{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T05:01:48Z","timestamp":1769317308021,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":516,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["7R01DE018386-03"],"award-info":[{"award-number":["7R01DE018386-03"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head Neck"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1002\/hed.23608","type":"journal-article","created":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T21:54:47Z","timestamp":1389650087000},"page":"327-335","source":"Crossref","is-referenced-by-count":29,"title":["CD200: Association with cancer stem cell features and response to chemoradiation in head and neck squamous cell carcinoma"],"prefix":"10.1002","volume":"37","author":[{"given":"Yuh-Seog","family":"Jung","sequence":"first","affiliation":[{"name":"Head and Neck Oncology Clinic; Center for Thyroid Cancer; Department of Otolaryngology; Research Institute and Hospital; National Cancer Center; Goyang Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola D.","family":"Vermeer","sequence":"additional","affiliation":[{"name":"Sanford Cancer Research Center; Sanford ENT - Head and Neck Surgery; University of South Dakota; Sioux Falls South Dakota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel W.","family":"Vermeer","sequence":"additional","affiliation":[{"name":"Sanford Cancer Research Center; Sanford ENT - Head and Neck Surgery; University of South Dakota; Sioux Falls South Dakota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Jin","family":"Lee","sequence":"additional","affiliation":[{"name":"Genitourinary Cancer Branch; Research Institute and Hospital; National Cancer Center; Goyang Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ah Ra","family":"Goh","sequence":"additional","affiliation":[{"name":"Genitourinary Cancer Branch; Research Institute and Hospital; National Cancer Center; Goyang Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun-Joo","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology; Sungkyunkwan University, Samsung Medical Center; Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Sanford Cancer Research Center; Sanford ENT - Head and Neck Surgery; University of South Dakota; Sioux Falls South Dakota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,3]]},"reference":[{"key":"10.1002\/hed.23608-BIB0001|hed23608-cit-0001","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1471-2407-2-37","article-title":"Global and regional estimates of cancer mortality and incidence by site: II. Results for the global burden of disease 2000","volume":"2","author":"Shibuya","year":"2002","journal-title":"BMC Cancer"},{"key":"10.1002\/hed.23608-BIB0002|hed23608-cit-0002","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1093\/annonc\/mdn372","article-title":"HPV in oral squamous cell carcinoma vs head and neck squamous cell carcinoma biopsies: a meta-analysis (1988-2007)","volume":"19","author":"Termine","year":"2008","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.23608-BIB0003|hed23608-cit-0003","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/ijc.24339","article-title":"Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma?","volume":"125","author":"N\u00e4sman","year":"2009","journal-title":"Int J Cancer"},{"key":"10.1002\/hed.23608-BIB0004|hed23608-cit-0004","doi-asserted-by":"crossref","first-page":"5630","DOI":"10.1200\/JCO.2005.04.6136","article-title":"High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma","volume":"24","author":"Licitra","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.23608-BIB0005|hed23608-cit-0005","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/nature05236","article-title":"Glioma stem cells promote radioresistance by preferential activation of the DNA damage response","volume":"444","author":"Bao","year":"2006","journal-title":"Nature"},{"key":"10.1002\/hed.23608-BIB0006|hed23608-cit-0006","doi-asserted-by":"crossref","first-page":"309","DOI":"10.4161\/cc.7.3.5389","article-title":"IL-4-mediated drug resistance in colon cancer stem cells","volume":"7","author":"Todaro","year":"2008","journal-title":"Cell Cycle"},{"key":"10.1002\/hed.23608-BIB0007|hed23608-cit-0007","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.it.2008.07.005","article-title":"Cancer stem cells, CD200 and immunoevasion","volume":"29","author":"Kawasaki","year":"2008","journal-title":"Trends Immunol"},{"key":"10.1002\/hed.23608-BIB0008|hed23608-cit-0008","first-page":"149","article-title":"Neuronal\/lymphoid membrane glycoprotein MRC OX-2 is a member of the immunoglobulin superfamily with a light-chain-like structure","volume":"51","author":"Barclay","year":"1986","journal-title":"Biochem Soc Symp"},{"key":"10.1002\/hed.23608-BIB0009|hed23608-cit-0009","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1046\/j.1365-2567.2001.01163.x","article-title":"The unusual distribution of the neuronal\/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans","volume":"102","author":"Wright","year":"2001","journal-title":"Immunology"},{"key":"10.1002\/hed.23608-BIB0010|hed23608-cit-0010","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1126\/science.290.5497.1768","article-title":"Down-regulation of the macrophage lineage through interaction with OX2 (CD200)","volume":"290","author":"Hoek","year":"2000","journal-title":"Science"},{"key":"10.1002\/hed.23608-BIB0011|hed23608-cit-0011","doi-asserted-by":"crossref","first-page":"191","DOI":"10.4049\/jimmunol.176.1.191","article-title":"Regulation of myeloid cell function through the CD200 receptor","volume":"176","author":"Jenmalm","year":"2006","journal-title":"J Immunol"},{"key":"10.1002\/hed.23608-BIB0012|hed23608-cit-0012","first-page":"483","article-title":"CD200 and its receptors as targets for immunoregulation","volume":"6","author":"Gorczynski","year":"2005","journal-title":"Curr Opin Investig Drugs"},{"key":"10.1002\/hed.23608-BIB0013|hed23608-cit-0013","doi-asserted-by":"crossref","first-page":"774","DOI":"10.4049\/jimmunol.162.2.774","article-title":"Evidence that an OX-2-positive cell can inhibit the stimulation of type 1 cytokine production by bone marrow-derived B7-1 (and B7-2)-positive dendritic cells","volume":"162","author":"Gorczynski","year":"1999","journal-title":"J Immunol"},{"key":"10.1002\/hed.23608-BIB0014|hed23608-cit-0014","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0041-1345(98)01563-2","article-title":"Anti-rat OX-2 blocks increased small intestinal transplant survival after portal vein immunization","volume":"31","author":"Gorczynski","year":"1999","journal-title":"Transplant Proc"},{"key":"10.1002\/hed.23608-BIB0015|hed23608-cit-0015","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.bbrc.2007.11.103","article-title":"CD200: a putative therapeutic target in cancer","volume":"366","author":"Moreaux","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1002\/hed.23608-BIB0016|hed23608-cit-0016","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1073\/pnas.0510081103","article-title":"Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation","volume":"103","author":"McWhirter","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1002\/hed.23608-BIB0017|hed23608-cit-0017","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/sj.leu.2404559","article-title":"CD200 as a prognostic factor in acute myeloid leukaemia","volume":"21","author":"Tonks","year":"2007","journal-title":"Leukemia"},{"key":"10.1002\/hed.23608-BIB0018|hed23608-cit-0018","doi-asserted-by":"crossref","first-page":"4194","DOI":"10.1182\/blood-2006-06-029355","article-title":"CD200 is a new prognostic factor in multiple myeloma","volume":"108","author":"Moreaux","year":"2006","journal-title":"Blood"},{"key":"10.1002\/hed.23608-BIB0019|hed23608-cit-0019","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.bbrc.2007.10.067","article-title":"Co-expression of the toleragenic glycoprotein, CD200, with markers for cancer stem cells","volume":"364","author":"Kawasaki","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1002\/hed.23608-BIB0020|hed23608-cit-0020","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.2174\/092986708786848541","article-title":"Cancer stem cells: how can we target them?","volume":"15","author":"Ischenko","year":"2008","journal-title":"Curr Med Chem"},{"key":"10.1002\/hed.23608-BIB0021|hed23608-cit-0021","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/abbs\/gmp040","article-title":"Bmi-1, stem cells and cancer","volume":"41","author":"Jiang","year":"2009","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"10.1002\/hed.23608-BIB0022|hed23608-cit-0022","doi-asserted-by":"crossref","first-page":"e31442","DOI":"10.1371\/journal.pone.0031442","article-title":"Melanoma cell expression of CD200 inhibits tumor formation and lung metastasis via inhibition of myeloid cell functions","volume":"7","author":"Talebian","year":"2012","journal-title":"PLoS One"},{"key":"10.1002\/hed.23608-BIB0023|hed23608-cit-0023","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1001\/archotol.133.5.495","article-title":"The role of human papillomavirus 16 E6 in anchorage-independent and invasive growth of mouse tonsil epithelium","volume":"133","author":"Hoover","year":"2007","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1002\/hed.23608-BIB0024|hed23608-cit-0024","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nature04873","article-title":"Validating cancer drug targets","volume":"441","author":"Benson","year":"2006","journal-title":"Nature"},{"key":"10.1002\/hed.23608-BIB0025|hed23608-cit-0025","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1001\/archoto.2009.159","article-title":"Immune response during therapy with cisplatin or radiation for human papillomavirus-related head and neck cancer","volume":"135","author":"Spanos","year":"2009","journal-title":"Arch Otolaryngol Head Neck Surg"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23608","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/hed.23608\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,9]],"date-time":"2023-07-09T19:44:23Z","timestamp":1688931863000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23608"}},"subtitle":["CD200 in Oropharyngeal Cancer"],"short-title":[],"issued":{"date-parts":[[2014,4,3]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"URL":"https:\/\/doi.org\/10.1002\/hed.23608","relation":{},"ISSN":["1043-3074"],"issn-type":[{"value":"1043-3074","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4,3]]}}}