{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T23:41:11Z","timestamp":1788392471940,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,6,19]],"date-time":"2014-06-19T00:00:00Z","timestamp":1403136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to report the long\u2010term outcome of patients with squamous cell cancer (SCC) of the tonsil managed by surgery followed by postoperative radiotherapy (PORT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010eight patients treated between 1985 and 2005 were analyzed. Overall survival (OS), disease\u2010specific survival (DSS), and recurrence\u2010free survival (RFS) were determined by the Kaplan\u2013Meier method. Factors predictive of outcome were determined by univariate and multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010eight percent of patients had T3 to T4 disease and 75% had a positive neck. Five\u2010year OS, DSS, and RFS were 66%, 82%, and 80%, respectively. The status of the neck was not predictive of outcome (DSS 80% for N0 vs 82% for N+; <jats:italic>p<\/jats:italic> = .97). Lymphovascular invasion was an independent predictor of OS, DSS, and RFS on multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Lymphovascular invasion but not pathological stage of the neck is an independent predictor of outcome in patients with tonsillar SCC. \u00a9 2014 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 37: 800\u2013807, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23679","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T09:32:21Z","timestamp":1394530341000},"page":"800-807","source":"Crossref","is-referenced-by-count":13,"title":["Squamous cell carcinoma of the tonsil managed by conventional surgery and postoperative radiation"],"prefix":"10.1002","volume":"37","author":[{"given":"Rahmatullah","family":"Rahmati","sequence":"first","affiliation":[{"name":"Head and Neck Service Department of Surgery Memorial Sloan\u2013Kettering Cancer Center New York New 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