{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:13:13Z","timestamp":1777479193060,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,6,30]],"date-time":"2014-06-30T00:00:00Z","timestamp":1404086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Surgery followed by radiotherapy (RT) is indicated for patients with high\u2010risk oral cavity cancer (OCC). Based on multi\u2010institutional reports, we developed a guideline for postoperative RT for patients with OCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multidisciplinary OCC team was recruited to develop a questionnaire concerning details of risk\u2010factor categorization, target delineation, and dose specification. Thirty\u2010one radiation oncologists from 18 institutions completed the questionnaire, and data were subjected to extensive review to establish the guideline by expert meeting. In this study, we also report the results for patients treated in accordance with the guideline at our institution between 2007 and 2011.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one patients received RT compatible with this guideline with a median 26.8\u2010month follow\u2010up. Thirty\u2010two patients (78%) remained disease\u2010free, 6 (15%) developed locoregional recurrence (4 in\u2010field, 1 marginal, and 1 out\u2010field) and 4 (10%) developed distant metastasis. The overall 2\u2010year survival rate was 86.7%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This guideline is promising and should be validated and refined in further clinical practice. \u00a9 2014 Wiley Periodicals, Inc. Head Neck 37: 933\u2013939, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23692","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T09:26:39Z","timestamp":1394789199000},"page":"933-939","source":"Crossref","is-referenced-by-count":20,"title":["Guideline and preliminary clinical practice results for dose specification and target delineation for postoperative radiotherapy for oral cavity cancer"],"prefix":"10.1002","volume":"37","author":[{"given":"Shih\u2010Hua","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.S. Clifford","family":"Chao","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Columbia University New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Shing","family":"Leu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jehn\u2010Chuan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung\u2010Ji","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Chuen","family":"Huang","sequence":"additional","affiliation":[{"name":"Graduate Institute of Chinese Medical Science China Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Fang","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong\u2010Wen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u2010Ting","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Taipei Medical University\u2013Shuang Ho Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Jen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mackay Memorial Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2008.05.023"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032641"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032646"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20279"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01749-7"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(96)00264-7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00585-X"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(01)00111-7"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0748-7983(96)92969-8"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00550-7"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(03)00405-X"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)03940-8"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.11.030"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-2-16"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.05.024"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2010.04.031"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e3181c4c3cc"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.08.020"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23692","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T01:34:01Z","timestamp":1696469641000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,30]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1002\/hed.23692"],"URL":"https:\/\/doi.org\/10.1002\/hed.23692","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,30]]}}}