{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:56:56Z","timestamp":1791475016175,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,1,27]],"date-time":"2015-01-27T00:00:00Z","timestamp":1422316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Anaplastic thyroid carcinoma (ATC) is an uncommon thyroid malignancy with a poor prognosis. American Thyroid Association (ATA) guidelines acknowledge the complexity of airway management in these patients. We studied our local experience with the aim of providing guidance in airway management in ATC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with histologically confirmed ATC from January 2004 to December 2011 were identified from our institutional database. The data were retrospectively analyzed using hospital case notes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010six patients were identified with ATC, 25 of who died from the disease. Five of 26 patients (19%) had stridor at presentation. A further 6 of 26 patients (23%) developed stridor during or soon after radiotherapy. Nine patients (36%) died of airway obstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tracheotomy can facilitate completion of palliative treatment in those patients with ATC and stridor. Given the short life expectancy of these patients, a balanced decision must be made regarding the role and timing of tracheotomy. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 38: 85\u201388, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23857","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T10:19:38Z","timestamp":1410517178000},"page":"85-88","source":"Crossref","is-referenced-by-count":30,"title":["Management of the compromised airway and role of tracheotomy in anaplastic thyroid carcinoma"],"prefix":"10.1002","volume":"38","author":[{"given":"Navin","family":"Mani","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Christie Hospital Manchester United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"McNamara","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University Hospital of South Manchester Manchester United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Lowe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Christie Hospital Manchester United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Loughran","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Central Manchester University Hospitals Manchester United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beng K.","family":"Yap","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology The Christie Hospital Manchester United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2388(199901\/02)16:1<64::AID-SSU10>3.0.CO;2-U"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e328343af3d"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0302"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2004.03062.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/110241500750009672"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.05.042"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-007-0776-7"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3181726d36"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880170109"},{"key":"e_1_2_6_11_1","first-page":"260","article-title":"Reinterventions in anaplastic cancers and sarcomas of the thyroid gland [in German]","volume":"102","author":"Hermann M","year":"1990","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_6_12_1","first-page":"264","article-title":"Status of tracheostomy in treatment of the respiratory emergency in anaplastic thyroid cancer [in German]","volume":"102","author":"H\u00f6lting T","year":"1990","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01261613"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2008.02.003"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0332"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23857","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23857","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T01:26:13Z","timestamp":1696382773000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,27]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1002\/hed.23857"],"URL":"https:\/\/doi.org\/10.1002\/hed.23857","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,27]]}}}