{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:56:43Z","timestamp":1760299003025},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T00:00:00Z","timestamp":1432252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Institute of Medical Statistics, Informatics and Epidemiology (IMSIE)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Health\u2010related quality of life (HRQOL) has received more and more attention as an outcome in cancer therapy. In this exploratory study, we assessed the long\u2010term HRQOL among 77 surgically treated patients with parotid gland cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire\u2010Core 30\u2010questions (EORTC\u2010QLQ\u2010C30) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire\u2010Core 30 Head and Neck 35\u2010questions (EORTC\u2010QLQ\u2010C30\u2010H&amp;N35) questionnaires were used in a cross\u2010sectional design. The mean time\u2010lag between initial diagnosis and completion of the questionnaire was 89.7 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The HRQOL significantly increased with the time\u2010lag to surgery and decreased with the patients' age. Factors with clinically significant effects in several areas of long\u2010term HRQOL (ie, more than 4 scores) were age, type of neck dissection, preoperative facial nerve palsy, and postoperative radiation therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In parotid gland cancer surgery, factors, such as sex, age, type of surgery, facial nerve palsy, and radiation therapy, seem to be associated with clinically meaningful differences in long\u2010term HRQOL scores. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 38: 111\u2013117, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23858","type":"journal-article","created":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T09:04:24Z","timestamp":1410858264000},"page":"111-117","source":"Crossref","is-referenced-by-count":10,"title":["Exploratory study of long\u2010term health\u2010related quality of life in patients with surgically treated primary parotid gland cancer"],"prefix":"10.1002","volume":"38","author":[{"given":"Markus","family":"Stenner","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of M\u00fcnster M\u00fcnster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Beenen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moritz","family":"Hahn","sequence":"additional","affiliation":[{"name":"Institute of Medical Statistics, Informatics and Epidemiology (IMSIE), University Hospital of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Koopmann","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of M\u00fcnster M\u00fcnster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of M\u00fcnster M\u00fcnster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl\u2010Bernd","family":"H\u00fcttenbrink","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,22]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"209","volume-title":"Tumours of the salivary gland. 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