{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T13:44:11Z","timestamp":1782999851295,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,16]],"date-time":"2015-06-16T00:00:00Z","timestamp":1434412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Controversy exists regarding the functional advantages of free flap reconstruction after partial glossectomy as compared to primary closure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty patients were included in this retrospective analysis after resection of pT3 lateral tongue carcinomas. Twenty patients received a free forearm flap and 20 patients had a primary closure. All patients had adjuvant chemoradiation, were free of disease at least 1 year after therapy, and completed the German versions of the European Organization for Research and Treatment of Cancer (EORTC) questionnaires Quality of Life Questionnaire\u2010Core 30\u2010questions (QLQ\u2010C30) and Quality of Life Questionnaire\u2010Core 30 Head and Neck 35\u2010questions (QLQ\u2010H&amp;N35).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean time between surgery and quality of life (QOL) assessment was 16.2\u2009\u00b1\u20093.4 months. The average resection was 41.60% (reconstruction) of the oral tongue, and 39.1% (primary closure). After reconstruction, patients had significantly (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05) fewer problems with the swallowing, speech, and social eating subdomains of the EORTC QLQ\u2010H&amp;N35. All other items showed no significant differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our preliminary results suggest that free flaps might be useful when treating pT3 tongue cancer. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 38: 89\u201394, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23862","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T16:42:49Z","timestamp":1410799369000},"page":"89-94","source":"Crossref","is-referenced-by-count":50,"title":["Quality of life in patients after resection of pT3 lateral tongue carcinoma: Microvascular reconstruction versus primary closure"],"prefix":"10.1002","volume":"38","author":[{"given":"Martin","family":"Canis","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of G\u00f6ttingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard G.","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of G\u00f6ttingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedrich","family":"Ihler","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of G\u00f6ttingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Hummers\u2013Pradier","sequence":"additional","affiliation":[{"name":"Department of General Practice\/Family Medicine University of G\u00f6ttingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Matthias","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of G\u00f6ttingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik A.","family":"Wolff","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of G\u00f6ttingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-10-134"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.04.005"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2592-z"},{"issue":"1","key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1288\/00005537-199401000-00015","article-title":"Surgical variables affecting postoperative swallowing efficiency in oral cancer patients: a pilot study","volume":"104","author":"McConnel FM","year":"1994","journal-title":"Laryngoscope"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199605\/06)18:3<259::AID-HED8>3.0.CO;2-Z"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2006.11.017"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.6.625"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31828f1a6b"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.07.011"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1994.01880300007002"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215108003629"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25537"},{"key":"e_1_2_6_14_1","first-page":"100","volume-title":"Endoscopic laser surgery of the upper aerodigestive tract","author":"Steiner W","year":"2000"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.5.365"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2006.01256.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21431"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1987.01860050042011"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e3281fbd406"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199909010-00006"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.06.058"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23268"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2007.43"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(99)80049-3"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3181644abd"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2014.01.002"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2006.10.018"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2005.09.005"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23862","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T01:25:42Z","timestamp":1696382742000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,16]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1002\/hed.23862"],"URL":"https:\/\/doi.org\/10.1002\/hed.23862","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,16]]}}}