{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:34:21Z","timestamp":1757313261980},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T00:00:00Z","timestamp":1432598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head & Neck"],"published-print":{"date-parts":[[2015,8]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Radiation\u2010induced salivary gland tumors are well described in the literature, with mucoepidermoid cancer being the most common histologic entity. Epithelial\u2010myoepithelial carcinoma is a rare tumor accounting for <1% of all tumors in the salivary glands.<\/jats:p><\/jats:sec>Methods and Results<\/jats:title>We describe the first case of radiation\u2010induced epithelial\u2010myoepithelial carcinoma in the English\u2010language medical literature. A 48\u2010year\u2010old man presented with right\u2010sided mandibular pain and trismus, 25 years after mantle\u2010field radiation therapy (RT) for Hodgkin lymphoma. He underwent excision of a right submandibular mass, which revealed a diagnosis of epithelial\u2010myoepithelial carcinoma. Although typically a low\u2010grade tumor, the histology revealed extensive necrosis and high mitotic activity. The patient required multiple resections and adjuvant therapy after multiple recurrences over a 4\u2010year period.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Reports of epithelial\u2010myoepithelial carcinoma are relatively rare and this case highlights the importance of long\u2010term follow\u2010up and increased awareness of the risks of salivary gland tumors in this population. \u00a9 2014 Wiley Periodicals, Inc. Head Neck<\/jats:italic> 37:<\/jats:bold> E96\u2013E98, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.23873","type":"journal-article","created":{"date-parts":[[2014,9,20]],"date-time":"2014-09-20T08:49:32Z","timestamp":1411202972000},"source":"Crossref","is-referenced-by-count":3,"title":["Radiation\u2010induced epithelial\u2010myoepithelial carcinoma in a patient previously treated with mantle\u2010field radiation therapy for Hodgkin lymphoma"],"prefix":"10.1002","volume":"37","author":[{"given":"Justin M.","family":"Mann","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology SUNY Upstate Medical University Syracuse New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Kellman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Communication Sciences SUNY Upstate Medical University Syracuse New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung S.","family":"Hahn","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology SUNY Upstate Medical University Syracuse New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo L.","family":"de la Roza","sequence":"additional","affiliation":[{"name":"Department of Pathology SUNY Upstate Medical University Syracuse New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajeet","family":"Gajra","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology SUNY Upstate Medical University Syracuse New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,26]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00543554"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23026"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.08.021"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199807000-00026"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.2307\/3579392"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23918"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00130404-200311000-00006"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.44.5.419"},{"key":"e_1_2_4_10_1","first-page":"WMC002566","article-title":"Epithelial\u2010myoepithelial carcinoma of parotid\u2013a rare case report","volume":"2","author":"Mahapatra S","year":"2011","journal-title":"Webmedcentral"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100134085"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e366d2"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213314.74423.d8"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01605458"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980101)82:1<8::AID-CNCR3>3.0.CO;2-W"}],"container-title":["Head & Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.23873","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.23873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T01:03:48Z","timestamp":1696467828000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.23873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,26]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1002\/hed.23873"],"URL":"https:\/\/doi.org\/10.1002\/hed.23873","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,26]]}}}