{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T15:42:28Z","timestamp":1793374948991,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T00:00:00Z","timestamp":1434326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Center for Diagnostic and Therapeutic Radiology, University of Freiburg"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Aberrant internal carotid arteries (ICAs) are not rare anatomic variations. The purpose of this study was for us to highlight their relevance and underline the need for a clinical grading system in addition to the currently used anatomic classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This systematic quality assessment study over 7 years includes 125 adults with 231 aberrant ICAs. Digital imaging datasets were analyzed and ICAs classified according to the anatomic classification in tortuosity, kinking, and coiling. Risk potential for ICA injury was estimated from the vessel's relation to the pharynx and neck.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis revealed a high frequency of medial and lateral ICA aberrations that seem surgically relevant, but the risk potential for injury was not reflected by the anatomic classification. Our previously proposed clinical grading system was reviewed and updated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Aberrant ICAs are underestimated anatomic variations with high clinical impact for transoral and transcervical interventions. The introduced clinicoradiologic grading system could be of major benefit. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>38<\/jats:bold>: E687\u2013E693, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24071","type":"journal-article","created":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T14:50:56Z","timestamp":1429541456000},"source":"Crossref","is-referenced-by-count":28,"title":["Aberrant extracranial internal carotid arteries: New insights, implications, and demand for a clinical grading system"],"prefix":"10.1002","volume":"38","author":[{"given":"Jens","family":"Pfeiffer","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd J.","family":"Ridder","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,15]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"601","article-title":"The \"dangerous loop\" of the internal carotid artery. An anatomic study [in German]","volume":"43","author":"Tillmann B","year":"1995","journal-title":"HNO"},{"key":"e_1_2_6_3_1","first-page":"85","article-title":"Abnormal tortuosity of the internal carotid artery and its clinical significance in surgery of the neck area [in German]","volume":"48","author":"Herrschaft H","year":"1969","journal-title":"Z Laryngol Rhinol Otol"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890120066013"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-7580.2000.19730373.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.07.002"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001060050187"},{"key":"e_1_2_6_8_1","first-page":"178","article-title":"Current aspects in diagnosis and therapy of carotid artery kinking [in German]","volume":"44","author":"Schenk P","year":"1996","journal-title":"HNO"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(00)80125-8"},{"key":"e_1_2_6_10_1","first-page":"294","article-title":"Radiology case of the month. Aberrant internal carotid artery manifesting as a pharyngeal mass","volume":"21","author":"Hertzanu Y","year":"1992","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_11_1","first-page":"117","article-title":"Extracranial arterial anomalies and forensic implications in surgery [in German]","volume":"19","author":"Riemann D","year":"1971","journal-title":"HNO"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.10.005"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.15.5.462"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.15.1.7"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318180213b"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(61)90004-6"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2010.03.006"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003319709336417"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-006-0149-1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0398-6"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2005.07.034"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.33.2.194"},{"key":"e_1_2_6_23_1","first-page":"43","article-title":"Surgical approach to kinking and coiling of the internal carotid artery","volume":"45","author":"Aleksic M","year":"2004","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181865913"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940211100216"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-012-1047-3"},{"key":"e_1_2_6_27_1","first-page":"E15","article-title":"Internal carotid artery in zone IIb and its implications: a case report","volume":"92","author":"Plonk DP","year":"2013","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1989.01860280117029"},{"key":"e_1_2_6_29_1","first-page":"33","article-title":"Aberrant internal carotid artery presenting in the midline retropharyngeal space: case report","volume":"48","author":"Miller S","year":"1997","journal-title":"Can Assoc Radiol J"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23393"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.24071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.24071","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.24071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T01:59:13Z","timestamp":1694311153000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.24071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,15]]},"references-count":29,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1002\/hed.24071"],"URL":"https:\/\/doi.org\/10.1002\/hed.24071","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,15]]}}}