{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T04:58:40Z","timestamp":1744347520481},"reference-count":32,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,7,15]],"date-time":"2015-07-15T00:00:00Z","timestamp":1436918400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Radioactive\u2010iodine remnant ablation is an integral part of the papillary thyroid carcinoma (PTC) treatment. Although a minimum dose is usually recommended, there is controversy as to whether the low\u2010dose (1100 MBq) radioactive\u2010iodine remnant ablation is adequate for selected patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study was conducted on 691 patients. Patients with no remnant thyroid on the follow\u2010up whole body scan and low stimulated thyroglobulin (sTg) level (&lt;2.0 ng\/mL) were deemed as successful treatment cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Initial low\u2010dose radioactive\u2010iodine remnant ablation was successful in 431 patients (62.3%). Multivariate analysis demonstrated a negative correlation between successful radioactive\u2010iodine remnant ablation and coexisting Hashimoto thyroiditis based on histopathology diagnosis (odds ratio [OR]\u2009=\u20093.23; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) as well as elevated preablation sTg (OR\u2009=\u20091.24; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our data suggest that coexisting Hashimoto thyroiditis and elevated sTg are negative predictive factors for successful low\u2010dose radioactive\u2010iodine remnant ablation treatment. An appropriate risk\u2010adjusted approach may improve the efficacy of radioactive\u2010iodine remnant ablation treatment. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>38<\/jats:bold>: E730\u2013E735, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24080","type":"journal-article","created":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T22:49:31Z","timestamp":1429570171000},"source":"Crossref","is-referenced-by-count":5,"title":["Effect of Hashimoto thyroiditis on low\u2010dose radioactive\u2010iodine remnant ablation"],"prefix":"10.1002","volume":"38","author":[{"given":"Hyungju","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Surgery Seoul National University Hospital and College of Medicine Seoul Korea"},{"name":"Department of Surgery Seoul National University Bundang Hospital and College of Medicine  Seongnam Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"June 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