{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:10:43Z","timestamp":1757311843899},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T00:00:00Z","timestamp":1441324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conflicting results are reported regarding the impact of neck dissection on radiation\u2010associated dysphagia. The purpose of this study was to reexamine this question specific to oropharyngeal intensity\u2010modulated radiotherapy (IMRT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three hundred forty\u2010nine patients with oropharyngeal cancer treated with bilateral IMRT with systemic therapy (induction and\/or concurrent) were reviewed. Chronic dysphagia was defined by aspiration, stricture, pneumonia, and\/or gastrostomy dependence \u226512 months post\u2010IMRT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Selective neck dissection was performed after IMRT in 75 patients (21%). Overall, 41 patients (12%) developed chronic dysphagia. Neck dissection did not increase the rate of chronic dysphagia (9% neck dissection; 12% no neck dissection; <jats:italic>p<\/jats:italic>\u2009=\u2009.464) or gastrostomy duration (<jats:italic>p<\/jats:italic>\u2009=\u2009.482). On multivariate analysis, age (odds ratio [OR] per 5\u2010year\u2009=\u20091.25; 95% confidence interval [CI]\u2009=\u20091.04\u20131.51), baseline abnormal diet (OR\u2009=\u20092.78; 95% CI\u2009=\u20091.31\u20135.88), and IMRT dose (OR per 5\u2010Gy\u2009=\u20095.11; 95% CI\u2009=\u20091.77\u201314.81) significantly predicted dysphagia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the setting of selective neck dissection for residual adenopathy after IMRT, neck dissection did not impact dysphagia. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 38: 886\u2013893, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24195","type":"journal-article","created":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T14:07:15Z","timestamp":1441375635000},"page":"886-893","source":"Crossref","is-referenced-by-count":11,"title":["Impact of selective neck dissection on chronic dysphagia after chemo\u2010intensity\u2010modulated radiotherapy for oropharyngeal carcinoma"],"prefix":"10.1002","volume":"38","author":[{"given":"Katherine A.","family":"Hutcheson","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal R.","family":"Abualsamh","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Sosa","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randal S.","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth M.","family":"Beadle","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erich M.","family":"Sturgis","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan S.","family":"Lewin","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21173"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.03.062"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21657"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.8841"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21188"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21275"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.04.048"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.10.1060"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.03.069"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2771"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2980"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.10.002"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2010.12.067"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2013.4715"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20299"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23200"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.0425"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23330"}],"container-title":["Head &amp; 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