{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:33:21Z","timestamp":1768869201377,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,11,28]],"date-time":"2015-11-28T00:00:00Z","timestamp":1448668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Whether elective lymph neck dissection (ELND) is associated with improved survival in oral squamous cell carcinomas (SCC) of the maxillary alveolus\/hard palate is not known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred ninety\u2010nine patients presenting de novo and receiving treatment for clinically node negative SCC of the maxillary alveolus\/hard palate at 2 cancer centers between 1985 and 2011 were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two patients (21%) received ELND. Occult nodal metastases were present in 29% of the dissected necks. The ELND group had more T3 to T4 status tumors (62% vs 34%; <jats:italic>p<\/jats:italic> &lt; .001) and positive\u2010margin resections (59% vs 38%; <jats:italic>p<\/jats:italic> = .019). Patients undergoing ELND experienced lower rates of neck recurrence (6% vs 21%; <jats:italic>p<\/jats:italic> = .031), superior 5\u2010year recurrence\u2010free survival (68% vs 45%; <jats:italic>p<\/jats:italic> = .026), and overall survival (86% vs 62%; <jats:italic>p<\/jats:italic> = .043). ELND was associated with a 2\u2010fold decrease in risk of recurrence in multivariable analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ELND was associated with lower rates of recurrence and improved survival in SCC of the maxillary alveolus\/hard palate. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>38<\/jats:bold>: E1688\u2013E1694, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24302","type":"journal-article","created":{"date-parts":[[2015,11,28]],"date-time":"2015-11-28T09:52:52Z","timestamp":1448704372000},"source":"Crossref","is-referenced-by-count":21,"title":["Impact of elective neck dissection on the outcome of oral squamous cell carcinomas arising in the maxillary alveolus and hard palate"],"prefix":"10.1002","volume":"38","author":[{"given":"Babak","family":"Givi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery New York University New York New 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