{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:10:28Z","timestamp":1773285028503,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T00:00:00Z","timestamp":1450915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The value of routine prophylactic antibiotic treatment in parotid gland surgery remains undetermined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was conducted of all patients who underwent parotidectomy at a university\u2010affiliated tertiary care center between 1992 and 2009. Patients with insufficient data, specifically regarding postoperative complications and antibiotic administration were excluded from the study cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 593 patients underwent parotidectomy during the study period. After exclusion, 464 patients were eligible for the study. Perioperative antibiotic treatment was given to 206 patients (45%). There was no difference in wound infection rates between patients who received perioperative antibiotic therapy and those who did not (<jats:italic>p<\/jats:italic> = .168). Multivariate analysis showed that female sex, neck dissection, and drain output &gt;50 cc\/24 hours were predictive of postoperative wound infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Routine prophylactic antibiotic treatment has no role in parotid gland surgery. Perioperative antibiotic treatment is recommended for patients undergoing extensive parotid gland surgery with neck dissection. \u00a9 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>38<\/jats:bold>: E1876\u2013E1880, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24339","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T14:02:05Z","timestamp":1450965725000},"source":"Crossref","is-referenced-by-count":12,"title":["Role of perioperative antibiotic treatment in parotid gland surgery"],"prefix":"10.1002","volume":"38","author":[{"given":"Yotam","family":"Shkedy","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uri","family":"Alkan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin R.","family":"Roman","sequence":"additional","affiliation":[{"name":"Head and Neck Service Department of Surgery Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ohad","family":"Hilly","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Feinmesser","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gideon","family":"Bachar","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aviram","family":"Mizrachi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv University Tel Aviv Israel"},{"name":"Head and Neck Service Department of Surgery Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2006.7.s2-37"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhin.2001.1122"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0588-x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1991.01870140082011"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1987.01860040030010"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199503000-00004"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318199f202"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/605926"},{"key":"e_1_2_6_10_1","first-page":"CD003949","article-title":"Preoperative skin antiseptics for preventing surgical wound infections after clean surgery","volume":"3","author":"Dumville JC","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu296"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000193183.30687.d5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2008.10.005"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2011.04.002"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.02.040"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2013.9999"},{"key":"e_1_2_6_17_1","first-page":"CD010268","article-title":"Antibiotic prophylaxis for the prevention of methicillin\u2010resistant Staphylococcus aureus (MRSA) related complications in surgical patients","volume":"8","author":"Gurusamy KS","year":"2013","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Head &amp; 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