{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T22:05:51Z","timestamp":1777327551065,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2016,2,2]],"date-time":"2016-02-02T00:00:00Z","timestamp":1454371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The best treatment for advanced tongue tumors remains controversial. Total glossectomy with laryngeal preservation is considered a feasible option, despite its morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of 12 total glossectomies with laryngeal preservation was performed in order to assess the available reconstruction techniques and analyze survival and functional outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One\u2010year overall survival (OS) and disease\u2010free survival (DFS) rates were 58.3% and 33.3%, respectively, both dropping to 25% after 3 years. Permanent gastrostomy was necessary in 10 patients, although videofluoroscopy revealed adequate tolerance to liquids. Speech intelligibility was satisfactory in 50% of the patients and severely impaired in the remaining 50%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Laryngeal preservation in the context of advanced tumors of the tongue without supraglottic invasion carried similar oncologic results to total glossectomy with laryngectomy, but offers a better phonatory function. However, it is usually associated with a higher gastrostomy dependency ratio. A scrupulous selection of candidates is mandatory. \u00a9 2016 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>38<\/jats:bold>: E2004\u2013E2010, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24369","type":"journal-article","created":{"date-parts":[[2016,2,2]],"date-time":"2016-02-02T16:44:59Z","timestamp":1454431499000},"source":"Crossref","is-referenced-by-count":13,"title":["Indications, reconstructive techniques, and results for total glossectomy"],"prefix":"10.1002","volume":"38","author":[{"given":"Alejandro","family":"Mazarro","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Department Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"de Pablo","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Department Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Puiggr\u00f2s","sequence":"additional","affiliation":[{"name":"Department of Nutrition Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00aa Mercedes","family":"Velasco","sequence":"additional","affiliation":[{"name":"Department of Phoniatry and Logopedy \u2013 Rehabilitation Service Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manel","family":"Saez","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Department Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Pamias","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Department Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coro","family":"Besc\u00f3s","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Department Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811412724"},{"key":"e_1_2_6_3_1","first-page":"22","article-title":"Is total glossectomy for advanced carcinoma of the tongue justified?","volume":"46","author":"Lierop AC","year":"2008","journal-title":"S Afr J Surg"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2004.02912.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199710000-00005"},{"key":"e_1_2_6_6_1","volume-title":"Multidisciplinary head and neck reconstruction. 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