{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:55:40Z","timestamp":1773924940849,"version":"3.50.1"},"reference-count":69,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head Neck"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1002\/hed.24423","type":"journal-article","created":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T11:31:40Z","timestamp":1462102300000},"page":"979-986","source":"Crossref","is-referenced-by-count":13,"title":["ACR Appropriateness criteria\u00ae for nasopharyngeal carcinoma"],"prefix":"10.1002","volume":"38","author":[{"given":"Nabil F.","family":"Saba","sequence":"first","affiliation":[{"name":"Emory University; Atlanta Georgia, American Society of Clinical Oncology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph K.","family":"Salama","sequence":"additional","affiliation":[{"name":"Duke University; Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan J.","family":"Beitler","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine; Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M.","family":"Busse","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital; Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay S.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Maimonides Cancer Center; Brooklyn New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher U.","family":"Jones","sequence":"additional","affiliation":[{"name":"Radiological Associates of Sacramento; Sacramento California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shlomo","family":"Koyfman","sequence":"additional","affiliation":[{"name":"Cleveland Clinic; Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Quon","sequence":"additional","affiliation":[{"name":"Johns Hopkins University; Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Ridge","sequence":"additional","affiliation":[{"name":"Fox Chase Cancer Center; Philadelphia Pennsylvania, American College of Surgeons"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzan","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Henry Ford Health System; Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Worden","sequence":"additional","affiliation":[{"name":"University of Michigan; Ann Arbor Michigan, American Society of Clinical Oncology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Yao","sequence":"additional","affiliation":[{"name":"University Hospitals Case Medical Center; Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue S.","family":"Yom","sequence":"additional","affiliation":[{"name":"University of California San Francisco; San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Expert Panel on Radiation Oncology-Head and Neck Cancer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,30]]},"reference":[{"key":"10.1002\/hed.24423-BIB0001|hed24423-cit-0001","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1158\/1055-9965.EPI-06-0353","article-title":"The enigmatic epidemiology of nasopharyngeal carcinoma","volume":"15","author":"Chang","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1002\/hed.24423-BIB0002|hed24423-cit-0002","first-page":"376","article-title":"Nasopharyngeal carcinoma: the Epstein-Barr virus association","volume":"21","author":"Liebowitz","year":"1994","journal-title":"Semin Oncol"},{"key":"10.1002\/hed.24423-BIB0003|hed24423-cit-0003","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1002\/(SICI)1097-0215(19981209)78:6<675::AID-IJC2>3.0.CO;2-J","article-title":"Diet and nasopharyngeal cancer in a low-risk population","volume":"78","author":"Farrow","year":"1998","journal-title":"Int J Cancer"},{"key":"10.1002\/hed.24423-BIB0004|hed24423-cit-0004","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/(SICI)1097-0215(20000201)85:3<358::AID-IJC11>3.0.CO;2-E","article-title":"Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China","volume":"85","author":"Yuan","year":"2000","journal-title":"Int J Cancer"},{"key":"10.1002\/hed.24423-BIB0005|hed24423-cit-0005","first-page":"587","article-title":"Nasopharyngeal cancer in a low-risk population: defining risk factors by histological type","volume":"5","author":"Vaughan","year":"1996","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1002\/hed.24423-BIB0006|hed24423-cit-0006","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.canep.2013.08.008","article-title":"Racial differences in nasopharyngeal carcinoma in the United States","volume":"37","author":"Wang","year":"2013","journal-title":"Cancer Epidemiol"},{"key":"10.1002\/hed.24423-BIB0007|hed24423-cit-0007","volume-title":"Pathology and Genetics of Head and Neck Tumours","author":"World Health Organization Classification of Tumours","year":"2005"},{"key":"10.1002\/hed.24423-BIB0008|hed24423-cit-0008","first-page":"4427","article-title":"Human papillomavirus and Epstein-Barr virus in epithelial carcinomas of the head and neck region","volume":"17","author":"Atula","year":"1997","journal-title":"Anticancer Res"},{"key":"10.1002\/hed.24423-BIB0009|hed24423-cit-0009","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1056\/NEJM199509143331103","article-title":"Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma","volume":"333","author":"Pathmanathan","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1002\/hed.24423-BIB0010|hed24423-cit-0010","first-page":"208","article-title":"The basaloid squamous cell carcinoma of the nasopharynx","volume":"38","author":"M\u00fcller","year":"2000","journal-title":"Rhinology"},{"key":"10.1002\/hed.24423-BIB0011|hed24423-cit-0011","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/1471-2407-12-98","article-title":"Patterns of regional lymph node metastasis of nasopharyngeal carcinoma: a meta-analysis of clinical evidence","volume":"12","author":"Ho","year":"2012","journal-title":"BMC Cancer"},{"key":"10.1002\/hed.24423-BIB0012|hed24423-cit-0012","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0360-3016(92)90740-9","article-title":"Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985: overall survival and patterns of failure","volume":"23","author":"Lee","year":"1992","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0013|hed24423-cit-0013","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1159\/000055743","article-title":"Distant metastases from nasopharyngeal cancer","volume":"63","author":"Chiesa","year":"2001","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"10.1002\/hed.24423-BIB0014|hed24423-cit-0014","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1056\/NEJMoa032260","article-title":"Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma","volume":"350","author":"Lin","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1002\/hed.24423-BIB0015|hed24423-cit-0015","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1093\/jnci\/94.21.1614","article-title":"Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma","volume":"94","author":"Chan","year":"2002","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/hed.24423-BIB0016|hed24423-cit-0016","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.ijrobp.2006.06.013","article-title":"Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial","volume":"66","author":"Pow","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0017|hed24423-cit-0017","doi-asserted-by":"crossref","first-page":"4873","DOI":"10.1200\/JCO.2007.11.5501","article-title":"Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients","volume":"25","author":"Kam","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0018|hed24423-cit-0018","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1245\/s10434-010-0985-4","article-title":"The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM","volume":"17","author":"Edge","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1002\/hed.24423-BIB0019|hed24423-cit-0019","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1748-717X-3-4","article-title":"Intensity-modulated radiotherapy of nasopharyngeal carcinoma: a comparative treatment planning study of photons and protons","volume":"3","author":"Taheri-Kadkhoda","year":"2008","journal-title":"Radiat Oncol"},{"key":"10.1002\/hed.24423-BIB0020|hed24423-cit-0020","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.ijrobp.2004.07.702","article-title":"Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience","volume":"61","author":"Lee","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"Suppl 5","key":"10.1002\/hed.24423-BIB0021|hed24423-cit-0021","doi-asserted-by":"crossref","first-page":"v187","DOI":"10.1093\/annonc\/mdq186","article-title":"Nasopharyngeal cancer: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"21","author":"Chan","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.24423-BIB0022|hed24423-cit-0022","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1093\/jnci\/djr432","article-title":"Concurrent chemoradiotherapy vs radiotherapy alone in stage II nasopharyngeal carcinoma: phase III randomized trial","volume":"103","author":"Chen","year":"2011","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/hed.24423-BIB0023|hed24423-cit-0023","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/hed.23386","article-title":"Clinical outcomes for early-stage nasopharyngeal carcinoma with predominantly WHO II histology treated by intensity-modulated radiation therapy with or without chemotherapy in nonendemic region of China","volume":"36","author":"Luo","year":"2014","journal-title":"Head Neck"},{"key":"10.1002\/hed.24423-BIB0024|hed24423-cit-0024","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/j.ijrobp.2006.02.016","article-title":"Improvement of survival after addition of induction chemotherapy to radiotherapy in patients with early-stage nasopharyngeal carcinoma: subgroup analysis of two phase III trials","volume":"65","author":"Chua","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0025|hed24423-cit-0025","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1200\/JCO.1998.16.4.1310","article-title":"Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099","volume":"16","author":"Al-Sarraf","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0026|hed24423-cit-0026","doi-asserted-by":"crossref","first-page":"6730","DOI":"10.1200\/JCO.2005.16.790","article-title":"Randomized trial of radiotherapy versus concurrent chemoradiotherapy followed by adjuvant chemotherapy in patients with American Joint Committee on Cancer\/International Union against cancer stage III and IV nasopharyngeal cancer of the endemic variety","volume":"23","author":"Wee","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0027|hed24423-cit-0027","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ijrobp.2005.06.037","article-title":"Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients","volume":"64","author":"Baujat","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0028|hed24423-cit-0028","doi-asserted-by":"crossref","first-page":"4604","DOI":"10.1200\/JCO.2004.10.074","article-title":"The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma: a meta-analysis of the published literature","volume":"22","author":"Langendijk","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0029|hed24423-cit-0029","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.ejca.2010.10.026","article-title":"Factors contributing to the efficacy of concurrent-adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma: combined analyses of NPC-9901 and NPC-9902 trials","volume":"47","author":"Lee","year":"2011","journal-title":"Eur J Cancer"},{"key":"10.1002\/hed.24423-BIB0030|hed24423-cit-0030","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1200\/JCO.2003.06.158","article-title":"Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: positive effect on overall and progression-free survival","volume":"21","author":"Lin","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0031|hed24423-cit-0031","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1080\/028418601750444105","article-title":"Neoadjuvant chemotherapy plus conventional radiotherapy or accelerated hyperfractionation in stage III and IV nasopharyngeal carcinoma-a phase II study","volume":"40","author":"El-Weshi","year":"2001","journal-title":"Acta Oncol"},{"key":"10.1002\/hed.24423-BIB0032|hed24423-cit-0032","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1748-717X-8-20","article-title":"Intensity modulated radiotherapy (IMRT) combined with concurrent but not adjuvant chemotherapy in primary nasopharyngeal cancer - a retrospective single center analysis","volume":"8","author":"Saleh-Ebrahimi","year":"2013","journal-title":"Radiat Oncol"},{"key":"10.1002\/hed.24423-BIB0033|hed24423-cit-0033","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s00432-012-1219-x","article-title":"Comparison of five cisplatin-based regimens frequently used as the first-line protocols in metastatic nasopharyngeal carcinoma","volume":"138","author":"Jin","year":"2012","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0034|hed24423-cit-0034","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/j.ejca.2007.03.022","article-title":"Chemoradiation comparing cisplatin versus carboplatin in locally advanced nasopharyngeal cancer: randomised, non-inferiority, open trial","volume":"43","author":"Chitapanarux","year":"2007","journal-title":"Eur J Cancer"},{"key":"10.1002\/hed.24423-BIB0035|hed24423-cit-0035","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1200\/JCO.2002.08.149","article-title":"Concurrent chemotherapy-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: progression-free survival analysis of a phase III randomized trial","volume":"20","author":"Chan","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0036|hed24423-cit-0036","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1093\/jnci\/dji084","article-title":"Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma","volume":"97","author":"Chan","year":"2005","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/hed.24423-BIB0037|hed24423-cit-0037","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/annonc\/mdr116","article-title":"Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation","volume":"23","author":"Fountzilas","year":"2012","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.24423-BIB0038|hed24423-cit-0038","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.ijrobp.2004.03.002","article-title":"Another way to estimate outcome of advanced nasopharyngeal carcinoma-is concurrent chemoradiotherapy adequate?","volume":"60","author":"Lin","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0039|hed24423-cit-0039","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S1470-2045(11)70320-5","article-title":"Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial","volume":"13","author":"Chen","year":"2012","journal-title":"Lancet Oncol"},{"key":"10.1002\/hed.24423-BIB0040|hed24423-cit-0040","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1002\/cncr.25932","article-title":"Plasma Epstein-Barr virus DNA level strongly predicts survival in metastatic\/recurrent nasopharyngeal carcinoma treated with palliative chemotherapy","volume":"117","author":"An","year":"2011","journal-title":"Cancer"},{"key":"10.1002\/hed.24423-BIB0041|hed24423-cit-0041","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1158\/1078-0432.CCR-12-3702","article-title":"An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma","volume":"19","author":"Le","year":"2013","journal-title":"Clin Cancer Res"},{"key":"10.1002\/hed.24423-BIB0042|hed24423-cit-0042","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1200\/JCO.2008.18.1545","article-title":"Randomized phase II trial of concurrent cisplatin-radiotherapy with or without neoadjuvant docetaxel and cisplatin in advanced nasopharyngeal carcinoma","volume":"27","author":"Hui","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0043|hed24423-cit-0043","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.ijrobp.2015.01.002","article-title":"Concurrent chemo-radiation with or without induction gemcitabine, carboplatin, and paclitaxel: a randomized, phase 2\/3 trial in locally advanced nasopharyngeal carcinoma","volume":"91","author":"Tan","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0044|hed24423-cit-0044","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1002\/cncr.29208","article-title":"Preliminary results of trial NPC-0501 evaluating the therapeutic gain by changing from concurrent-adjuvant to induction-concurrent chemoradiotherapy, changing from fluorouracil to capecitabine, and changing from conventional to accelerated radiotherapy fractionation in patients with locoregionally advanced nasopharyngeal carcinoma","volume":"121","author":"Lee","year":"2015","journal-title":"Cancer"},{"key":"10.1002\/hed.24423-BIB0045|hed24423-cit-0045","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1471-2407-6-28","article-title":"A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck","volume":"6","author":"Budach","year":"2006","journal-title":"BMC Cancer"},{"key":"10.1002\/hed.24423-BIB0046|hed24423-cit-0046","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.radonc.2010.09.023","article-title":"A randomized trial on addition of concurrent-adjuvant chemotherapy and\/or accelerated fractionation for locally-advanced nasopharyngeal carcinoma","volume":"98","author":"Lee","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1002\/hed.24423-BIB0047|hed24423-cit-0047","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.radonc.2007.01.013","article-title":"Results of a prospective randomised trial comparing conventional radiotherapy to split course bifractionated radiation therapy in patients with nasopharyngeal carcinoma","volume":"85","author":"Daoud","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1002\/hed.24423-BIB0048|hed24423-cit-0048","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0360-3016(00)00786-0","article-title":"Final report of a randomized trial on altered-fractionated radiotherapy in nasopharyngeal carcinoma prematurely terminated by significant increase in neurologic complications","volume":"48","author":"Teo","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0049|hed24423-cit-0049","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0360-3016(02)02724-4","article-title":"Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience","volume":"53","author":"Lee","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0050|hed24423-cit-0050","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1200\/JCO.2007.14.0285","article-title":"Improved survival after lymphadenectomy for nodal metastasis from an unknown primary melanoma","volume":"26","author":"Lee","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1002\/hed.24423-BIB0051|hed24423-cit-0051","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1016\/j.ijrobp.2012.09.033","article-title":"Replanning during intensity modulated radiation therapy improved quality of life in patients with nasopharyngeal carcinoma","volume":"85","author":"Yang","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0052|hed24423-cit-0052","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00280-012-2020-x","article-title":"Triplet combination with paclitaxel, cisplatin and 5-FU is effective in metastatic and\/or recurrent nasopharyngeal carcinoma","volume":"71","author":"Chen","year":"2013","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1002\/hed.24423-BIB0053|hed24423-cit-0053","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1056\/NEJMoa0802656","article-title":"Platinum-based chemotherapy plus cetuximab in head and neck cancer","volume":"359","author":"Vermorken","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1002\/hed.24423-BIB0054|hed24423-cit-0054","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00280-013-2196-8","article-title":"Polymorphisms in ERCC1 C8092A predict progression-free survival in metastatic\/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy","volume":"72","author":"Chen","year":"2013","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1002\/hed.24423-BIB0055|hed24423-cit-0055","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1368-8375(02)00120-3","article-title":"A phase II study of capecitabine in patients with recurrent and metastatic nasopharyngeal carcinoma pretreated with platinum-based chemotherapy","volume":"39","author":"Chua","year":"2003","journal-title":"Oral Oncol"},{"key":"10.1002\/hed.24423-BIB0056|hed24423-cit-0056","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/annonc\/mdf002","article-title":"Gemcitabine in metastatic nasopharyngeal carcinoma of the undifferentiated type","volume":"13","author":"Foo","year":"2002","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.24423-BIB0057|hed24423-cit-0057","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/cncr.20802","article-title":"Phase II study of irinotecan (CPT-11) as salvage therapy for advanced nasopharyngeal carcinoma","volume":"103","author":"Poon","year":"2005","journal-title":"Cancer"},{"key":"10.1002\/hed.24423-BIB0058|hed24423-cit-0058","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1093\/annonc\/mdq425","article-title":"Docetaxel is effective in heavily pretreated patients with disseminated nasopharyngeal carcinoma","volume":"22","author":"Ngeow","year":"2011","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.24423-BIB0059|hed24423-cit-0059","doi-asserted-by":"crossref","first-page":"5481","DOI":"10.1158\/1078-0432.CCR-10-3409","article-title":"A phase II study of pazopanib in Asian patients with recurrent\/metastatic nasopharyngeal carcinoma","volume":"17","author":"Lim","year":"2011","journal-title":"Clin Cancer Res"},{"key":"10.1002\/hed.24423-BIB0060|hed24423-cit-0060","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1093\/annonc\/mds581","article-title":"Phase II study of sorafenib in combination with cisplatin and 5-fluorouracil to treat recurrent or metastatic nasopharyngeal carcinoma","volume":"24","author":"Xue","year":"2013","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.24423-BIB0061|hed24423-cit-0061","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1093\/annonc\/mdq629","article-title":"Hemorrhagic complications in a phase II study of sunitinib in patients of nasopharyngeal carcinoma who has previously received high-dose radiation","volume":"22","author":"Hui","year":"2011","journal-title":"Ann Oncol"},{"key":"10.1002\/hed.24423-BIB0062|hed24423-cit-0062","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1007\/s00405-010-1385-x","article-title":"Current treatment options for recurrent nasopharyngeal cancer","volume":"267","author":"Suarez","year":"2010","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1002\/hed.24423-BIB0063|hed24423-cit-0063","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/hed.23403","article-title":"Multivariate analysis of prognostic factors for salvage nasopharyngectomy via the maxillary swing approach","volume":"36","author":"Chan","year":"2014","journal-title":"Head Neck"},{"key":"10.1002\/hed.24423-BIB0064|hed24423-cit-0064","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.ijrobp.2011.07.006","article-title":"Intensity-modulated radiation therapy in the salvage of locally recurrent nasopharyngeal carcinoma","volume":"83","author":"Qiu","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0065|hed24423-cit-0065","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0360-3016(97)00244-7","article-title":"Reirradiation for recurrent nasopharyngeal carcinoma: factors affecting the therapeutic ratio and ways for improvement","volume":"38","author":"Lee","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1002\/hed.24423-BIB0066|hed24423-cit-0066","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1186\/1748-717X-8-157","article-title":"Fractionated stereotactic radiotherapy for 136 patients with locally residual nasopharyngeal carcinoma","volume":"8","author":"Liu","year":"2013","journal-title":"Radiat Oncol"},{"key":"10.1002\/hed.24423-BIB0067|hed24423-cit-0067","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1002\/hed.23719","article-title":"Salvage endoscopic nasopharyngectomy and intensity-modulated radiotherapy versus conventional radiotherapy in treating locally recurrent nasopharyngeal carcinoma","volume":"37","author":"Zou","year":"2015","journal-title":"Head Neck"},{"key":"10.1002\/hed.24423-BIB0068|hed24423-cit-0068","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.radonc.2009.01.005","article-title":"GEC-ESTRO recommendations for brachytherapy for head and neck squamous cell carcinomas","volume":"91","author":"Mazeron","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1002\/hed.24423-BIB0069|hed24423-cit-0069","doi-asserted-by":"crossref","first-page":"6513","DOI":"10.7314\/APJCP.2013.14.11.6513","article-title":"Treatment outcome with brachytherapy for recurrent nasopharyngeal carcinoma","volume":"14","author":"Cheah","year":"2013","journal-title":"Asian Pac J Cancer Prev"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.24423","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/hed.24423","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T03:18:52Z","timestamp":1625282332000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.24423"}},"subtitle":["ACR Appropriateness Criteria\u00ae NPC"],"short-title":[],"issued":{"date-parts":[[2016,4,30]]},"references-count":69,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"URL":"https:\/\/doi.org\/10.1002\/hed.24423","archive":["Portico"],"relation":{},"ISSN":["1043-3074"],"issn-type":[{"value":"1043-3074","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4,30]]}}}