{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:16:51Z","timestamp":1771654611992,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,4,15]],"date-time":"2016-04-15T00:00:00Z","timestamp":1460678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Carcinosarcoma of the salivary glands is a rare neoplasm, and the minimally invasive form constitutes a subgroup with a more favorable prognosis. The cytomorphologic features of this neoplasm can be appreciated on fine\u2010needle aspiration biopsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>We present a patient with a minimally invasive carcinosarcoma ex non\u2010recurrent pleomorphic adenoma (Ca ex PA) who underwent initial fine\u2010needle aspiration biopsy followed by surgical resection. The tumor was composed predominantly of a light microscopic pleomorphic high\u2010grade sarcoma exhibiting partial myoepithelial immunohistochemical features, with a minor component of in situ and invasive salivary duct carcinoma (10%). A limited area with features of a hyalinized pleomorphic adenoma was identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the third case report of the cytological features of Ca ex PA of the salivary gland, with histologic correlation. It further illustrates the oncogenic relationship between epithelial and myoepithelial elements in the early stages of carcinosarcomatous transformation. \u00a9 2016 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>38:<\/jats:bold> E2483\u2013E2489, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24462","type":"journal-article","created":{"date-parts":[[2016,4,15]],"date-time":"2016-04-15T07:53:09Z","timestamp":1460706789000},"source":"Crossref","is-referenced-by-count":12,"title":["Minimally invasive carcinosarcoma ex pleomorphic adenoma: A case report and literature review with cytohistological correlation"],"prefix":"10.1002","volume":"38","author":[{"given":"Yingting","family":"Mok","sequence":"first","affiliation":[{"name":"Department of Pathology National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nga","family":"Min En","sequence":"additional","affiliation":[{"name":"Department of Pathology National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lim","family":"Chwee Ming","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fredrik","family":"Petersson","sequence":"additional","affiliation":[{"name":"Department of Pathology National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,15]]},"reference":[{"issue":"1","key":"e_1_2_4_2_1","first-page":"279","article-title":"Malignant mixed tumors of the salivary glands: a review","volume":"28","author":"Gnepp DR","year":"1993","journal-title":"Pathol Annu"},{"key":"e_1_2_4_3_1","volume-title":"Pathology and genetics of head and neck tumours","author":"Barnes L","year":"2005"},{"key":"e_1_2_4_4_1","first-page":"721","article-title":"Parotid tumors; 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