{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:07:44Z","timestamp":1788829664010,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,7,25]],"date-time":"2016-07-25T00:00:00Z","timestamp":1469404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The purpose of this study was to identify the factors influencing oncologic outcomes for patients with early\u2010intermediate glottic cancer treated by transoral laser microsurgery (TLM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective mono\u2010institutional study. A total of 590 patients with cTis\u2010cT3 glottic cancer underwent TLM with curative intent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>TLM alone was performed in 538 patients (91.2%) and TLM followed by adjuvant radiotherapy (RT) was done in 52 (8.8%). Five\u2010year recurrence\u2010free survival (RFS) and 10\u2010year overall survival (OS) were 85.3% and 74.7%, respectively. The larynx\u2010preservation ratio was 95.9%. In particular, from our data, we found that occult metastases were rare (1.2%); preventive tracheotomy was not necessary; the local recurrence rate of Tis was similar to that in the T2 and T3 group; and no major or lethal complications were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Age (&gt;60 vs \u226460), type of cordectomy (\u2265IV vs \u2264III), status of margins, fixed arytenoid, and pathologic T classification, were the variables associated with RFS, OS, and organ\u2010preservation rate. \u00a9 2016 Wiley Periodicals,\n                      <jats:italic>Head Neck<\/jats:italic>\n                      <jats:bold>39:<\/jats:bold>\n                      71\u201381, 2017\n                    <\/jats:p>\n                  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