{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T07:30:51Z","timestamp":1778657451453,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T00:00:00Z","timestamp":1477612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to investigate the impact of lymphocytic thyroiditis on incidence of incidental thyroid cancers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective review of 713 consecutive patients who underwent thyroidectomies. Incidental thyroid cancer was defined as an unexpected cancer discovered on pathological examination outside the index nodule undergoing preoperative cytology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We excluded 65 cases because of preoperative diagnosis of thyroid cancer, and 68 because of nonincidental cancer within the index nodule. Among the remaining 580 cases, there were 43 cases (7.4%) of incidental thyroid cancers. Incidental thyroid cancers were significantly associated with moderate\/severe lymphocytic thyroiditis (relative risk\u2009=\u20092.5; <jats:italic>p<\/jats:italic>\u2009=\u2009.03). Sixteen of 56 patients with moderate\/severe lymphocytic thyroiditis had Graves' disease, none of whom had incidental thyroid cancer. The risk of incidental thyroid cancer associated with moderate\/severe lymphocytic thyroiditis was significantly higher in non\u2010Graves' than patients with Graves' disease (<jats:italic>p<\/jats:italic>\u2009=\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The risk of incidental thyroid cancer is significantly increased in patients with moderate\/severe lymphocytic thyroiditis. Moderate\/severe lymphocytic thyroiditis associated with Graves' disease seems to have a lower risk of incidental thyroid cancer. \u00a9 2016 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>39:<\/jats:bold> 122\u2013127, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24544","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T14:47:02Z","timestamp":1477666022000},"page":"122-127","source":"Crossref","is-referenced-by-count":14,"title":["Impact of lymphocytic thyroiditis on incidence of pathological incidental thyroid carcinoma"],"prefix":"10.1002","volume":"39","author":[{"given":"Eric","family":"Farrell","sequence":"first","affiliation":[{"name":"School of Medicine University College Cork Cork Ireland United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Heffron","sequence":"additional","affiliation":[{"name":"Department of Pathology Cork University Hospital Cork Ireland United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Endocrinology South Infirmary Victoria University Hospital, Cork Cork Ireland United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"O'Leary","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery South Infirmary Victoria University Hospital, Cork Cork Ireland United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Sheahan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery South Infirmary Victoria University Hospital, Cork Cork Ireland United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2010.10.016"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.18.2164"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-3363-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-012-1021-x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812472426"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02848773"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2099.101431"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-014-1629-z"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.01.007"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19951201)76:11<2312::AID-CNCR2820761120>3.0.CO;2-H"},{"key":"e_1_2_6_12_1","unstructured":"StephensonTJ.Dataset for thyroid cancer histopathology reports. 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