{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T20:21:54Z","timestamp":1750537314459},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,9,12]],"date-time":"2016-09-12T00:00:00Z","timestamp":1473638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Rheumatoid nodules are a common manifestation of rheumatoid arthritis but buccal rheumatoid nodules are extremely rare. The purpose of this study was to report a rare case of a rheumatoid buccal nodule and a review of the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This case is about a 79\u2010year\u2010old woman with rheumatoid arthritis who was taking methotrexate and hydroxychloroquine, presenting with an enlarging left buccal submucosal mass. An incisional biopsy showed features consistent with that of a rheumatoid nodule. The mass was managed expectantly and the patient was taken off methotrexate with a marked reduction in the size of the nodule.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Submucosal rheumatoid nodules of the oral cavity are an extremely rare manifestation of rheumatoid arthritis but should be considered in the differential diagnosis in patients with a history of rheumatoid arthritis presenting with submucosal masses. \u00a9 2016 Wiley Periodicals, <jats:italic>Head Neck<\/jats:italic> <jats:bold>39<\/jats:bold>: E12\u2013E14, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24573","type":"journal-article","created":{"date-parts":[[2016,9,12]],"date-time":"2016-09-12T15:49:03Z","timestamp":1473695343000},"source":"Crossref","is-referenced-by-count":5,"title":["Rheumatoid nodule presenting as a buccal submucosal nodule: A rare presentation of a common disease"],"prefix":"10.1002","volume":"39","author":[{"given":"Gerald Ci\u2010An","family":"Tay","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Oregon Health and Science University Portland Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Sauer","sequence":"additional","affiliation":[{"name":"Department of Pathology Oregon Health and Science University Portland Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter E.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Oregon Health and Science University Portland Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199806)41:6<1072::AID-ART14>3.0.CO;2-G"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740310004621"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2015.03.004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.52.1.61"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1986.tb113669.x"},{"key":"e_1_2_5_7_1","first-page":"1960","article-title":"Rheumatoid nodulosis of the meninges","volume":"21","author":"Karam NE","year":"1994","journal-title":"J Rheumatol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.cr2012-0259"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem163"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.07.023"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90787-3"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009742.2010.509103"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196811000-00003"},{"key":"e_1_2_5_14_1","first-page":"770","article-title":"Lung biopsy in rheumatoid arthritis","volume":"131","author":"Yousem SA","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02030506"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.1-1-18"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002960050079"},{"key":"e_1_2_5_18_1","first-page":"103081","article-title":"Laryngeal manifestations of rheumatoid arthritis","volume":"2013","author":"Hamdan AL","year":"2013","journal-title":"Autoimmune Dis"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510014112X"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989570160-5"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780350025006"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1987.tb02074.x"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.03.034"},{"key":"e_1_2_5_24_1","first-page":"538","article-title":"Methotrexate induced accelerated nodulosis","volume":"52","author":"Agarwal V","year":"2004","journal-title":"J Assoc Physicians India"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.22.13.1157.33525"}],"container-title":["Head &amp; 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