{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T16:58:58Z","timestamp":1783097938835,"version":"3.54.6"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T00:00:00Z","timestamp":1482969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Science Technology Department of Zhejiang Province","award":["2015C33275"],"award-info":[{"award-number":["2015C33275"]}]},{"DOI":"10.13039\/501100014996","name":"Health and Family Planning Commission of Zhejiang Province","doi-asserted-by":"crossref","award":["2015KYB323"],"award-info":[{"award-number":["2015KYB323"]}],"id":[{"id":"10.13039\/501100014996","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to determine if ultrasound\u2010guided radiofrequency ablation (RFA) of hyperplastic parathyroid glands could be used to treat secondary hyperparathyroidism (HPT) in patients with chronic kidney disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>RFA of the hyperplastic parathyroid glands was performed in 34 patients with secondary HPT. Intact parathyroid hormone (iPTH), calcium, and phosphorus were measured. The outcome was based on the ablation extent (ie, 4, 3, and 1\u20132 glands).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The iPTH, calcium, and phosphorus levels decreased in all groups after RFA. One year after ablation, these parameters remained significantly lower in the 4\u2010gland ablation group compared with the 3\u2010gland and 1 to 2\u2010gland groups. The same tendency was observed for the symptom score. The iPTH levels of &lt;272 pg\/mL on the day after ablation was the best predictor for maintaining parathyroid hormone (PTH) levels in a reasonable range 1 year after ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RFA of hyperplastic parathyroid glands for treating secondary HPT is feasible in selected patients. \u00a9 2016 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> 39: 564\u2013571, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24657","type":"journal-article","created":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T13:23:27Z","timestamp":1483017807000},"page":"564-571","source":"Crossref","is-referenced-by-count":44,"title":["Efficacy and safety of ultrasound\u2010guided radiofrequency ablation of hyperplastic parathyroid gland for secondary hyperparathyroidism associated with chronic kidney disease"],"prefix":"10.1002","volume":"39","author":[{"given":"Chengzhong","family":"Peng","sequence":"first","affiliation":[{"name":"Department of Ultrasound Hangzhou Hospital of Traditional Chinese Medicine Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengxian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Hangzhou Hospital of Traditional Chinese Medicine Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jibin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology Thomas Jefferson University Hospital Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nephrology Hangzhou Hospital of Traditional Chinese Medicine Hangzhou Zhejiang Province 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