{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:43:36Z","timestamp":1786977816455,"version":"build-2736575974"},"reference-count":52,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T00:00:00Z","timestamp":1490659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006306","name":"Sigrid Jus\u00e9liuksen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006306","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Roughly half of submandibular gland neoplasms are malignant. Because preoperative information on the nature of these tumors remains limited, both preoperative evaluation and assessment of the extent of primary surgery warrant guidelines that are more accurate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We evaluated the preoperative examinations and management of all submandibular gland neoplasms treated surgically at the Helsinki University Hospital between 2000 and 2010.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 83 tumors, 58 (70%) were benign and 25 (30%) were malignant. Of the benign tumors, 54 (93%) were pleomorphic adenomas. The cytology in 8 patients (10%) was class IV or V, and in 12 patients was class III; the tumors in 9 of these 12 patients turned out to be malignant. Of all malignancies, 10 (40%) required additional more extensive surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Ultrasound\u2010guided fine\u2010needle aspiration cytology (FNAC) proved useful, with limitations, in preoperative examination. Surgeons should always obtain wide margins whenever possible, even when clinical means or cytology indicates no malignancy. \u00a9 2017 Wiley Periodicals, Inc.\n                      <jats:italic>Head Neck<\/jats:italic>\n                      <jats:bold>39:<\/jats:bold>\n                      1071\u20131077, 2017\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.24691","type":"journal-article","created":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T13:13:46Z","timestamp":1490706826000},"page":"1071-1077","source":"Crossref","is-referenced-by-count":33,"title":["Preoperative evaluation and surgical planning of submandibular gland tumors"],"prefix":"10.1002","volume":"39","author":[{"given":"Timo","family":"Atula","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Helsinki and Helsinki University Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha","family":"Panigrahi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Helsinki and Helsinki University Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussi","family":"Tarkkanen","sequence":"additional","affiliation":[{"name":"Department of Pathology HUSLAB, University of Helsinki and Helsinki University Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti","family":"M\u00e4kitie","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Helsinki and Helsinki University Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katri","family":"Aro","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Helsinki and Helsinki University Hospital Helsinki Finland"},{"name":"School of Dentistry University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00385.x"},{"key":"e_1_2_6_3_1","volume-title":"World Health Organization Classification of Tumours","author":"Barnes L","year":"2005"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2007.02.004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980401)82:7<1217::AID-CNCR2>3.0.CO;2-C"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20993"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23100"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2010.05347.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21151"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2520"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23613"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2009.10.004"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24247"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.08.001"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2008.02.004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.1.56"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.7.720"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0378-x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.09.029"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-011-0316-5"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2012.10.002"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2011.05.002"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e3181595ae0"},{"key":"e_1_2_6_24_1","first-page":"905","article-title":"Epidemiology, prognostic factors, and treatment of malignant submandibular gland tumors: a population\u2010based cohort analysis","volume":"141","author":"Lee RJ","year":"2015","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.208.2.9680573"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPOIE0CZNAT6SQ"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.09.064"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23193"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21821"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP5LTQ4RVOQAIT"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24339"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11101087"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP2SD8RFQEUZJW"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2014.07.001"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.6.541"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e328344f59c"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20829"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2716-5"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.03.017"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6306"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2013.01.009"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2007.06.012"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20865"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2005.11.018"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2013.11.002"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1392-y"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2014.02.015"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23733"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23523"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1586\/era.12.92"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10380"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)00122-F"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.05.024"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.24691","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.24691","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T08:24:48Z","timestamp":1695716688000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.24691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,28]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.1002\/hed.24691"],"URL":"https:\/\/doi.org\/10.1002\/hed.24691","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,28]]}}}