{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:04:16Z","timestamp":1777572256382,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T00:00:00Z","timestamp":1494201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Incidence rates for oral tongue squamous cell carcinoma (SCC) are steadily rising worldwide.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients diagnosed with primary oral tongue SCC at the 5 university hospitals in Finland from 2005 to 2009 were studied. The mean follow\u2010up time was 43 months (median, 54 months; range, 0\u2013111 months).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred sixty patients with primary oral tongue SCC were identified. Treatment with curative intent was provided for 328 patients (91%). The 5\u2010year disease\u2010specific survival (DSS) rates were as follows: stage I 87%; stage II 73%; stage III 69%; and stage IV 51%. The 5\u2010year recurrence\u2010free survival in general has improved from 47% in our previous published series (1995\u20131999) to 65% in the current series (<jats:italic>p<\/jats:italic> &lt; .001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The outcome of oral tongue SCC has significantly improved in Finland. However, the relatively high number of disease recurrences in patients with stage I and II disease, when compared with patients with stage III and IV disease, calls for an investigation of new treatment approaches. \u00a9 2017 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>39<\/jats:bold>: 1306\u20131312, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24744","type":"journal-article","created":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T14:33:04Z","timestamp":1494253984000},"page":"1306-1312","source":"Crossref","is-referenced-by-count":40,"title":["Improved outcomes with oral tongue squamous cell carcinoma in Finland"],"prefix":"10.1002","volume":"39","author":[{"given":"Rayan","family":"Mroueh","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery University of Helsinki and Helsinki University Hospital Helsinki 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