{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:45:57Z","timestamp":1764783957160},"reference-count":38,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T00:00:00Z","timestamp":1490745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to validate the prognostic value of adding narrow\u2010band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white\u2010light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence\u2010free survival were retrospectively compared between both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (<jats:italic>P<\/jats:italic> &lt; .01). Two\u2010year recurrence\u2010free survival was 82% in the WLI group and 98% in the NBI group (<jats:italic>P<\/jats:italic> &lt; .05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24773","type":"journal-article","created":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T06:46:49Z","timestamp":1490770009000},"page":"1343-1348","source":"Crossref","is-referenced-by-count":27,"title":["Narrow\u2010band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome"],"prefix":"10.1002","volume":"39","author":[{"given":"Boudewijn E. C.","family":"Plaat","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Groningen, University Medical Center Groningen  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manon A.","family":"Zwakenberg","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Groningen, University Medical Center Groningen  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joost G.","family":"van Zwol","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Groningen, University Medical Center Groningen  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Wedman","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Groningen, University Medical Center Groningen  The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard F. 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