{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T01:14:42Z","timestamp":1778980482081,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T00:00:00Z","timestamp":1493942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Unilateral radiotherapy (RT) of oropharyngeal carcinomas is accepted for patients with lateralized primary and low\u2010volume nodal disease. Utilizing prospectively defined criteria of laterality and staging positron emission tomography (PET)\/CT, we studied outcomes in patients with advanced\u2010stage oropharyngeal cancer undergoing unilateral RT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010seven patients with oropharyngeal tumors &gt;1 cm from midline regardless of node status underwent unilateral RT and were followed prospectively. Patient characteristics: T1 = 11; T2 = 22; T3 = 4; N0 = 3; N1 = 9; N2a = 3; N2b = 21; and Nx = 1. Dosimetry were determined and weekly National Comprehensive Cancer Network (NCCN) distress thermometer data were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At median follow\u2010up of 32 months, 3\u2010year locoregional control, contralateral regional failure, distant metastasis\u2010free survival, and disease\u2010free survival were 96%, 0%, 7%, and 93%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Low rates of contralateral neck failure are demonstrated utilizing prospectively defined criteria for unilateral RT. The tolerances of contralateral organs are respected and patients report low to moderate levels of distress throughout treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24806","type":"journal-article","created":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T06:42:41Z","timestamp":1493966561000},"page":"1647-1654","source":"Crossref","is-referenced-by-count":21,"title":["Low rates of contralateral neck failure in unilaterally treated oropharyngeal squamous cell carcinoma with prospectively defined criteria of lateralization"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4617-739X","authenticated-orcid":false,"given":"Kenneth Shung","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology New York University Langone Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waleed Fouad","family":"Mourad","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Georgia Regents University Augusta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0001-1653","authenticated-orcid":false,"given":"Mauricio","family":"Gamez","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic Scottsdale Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Safdieh","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mount Sinai at Beth Israel Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mount Sinai at Beth Israel Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam Saul","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York University Langone Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark Stephen","family":"Persky","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York University Langone Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark Lawrence","family":"Urken","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Mount Sinai at Beth Israel New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Culliney","sequence":"additional","affiliation":[{"name":"Department of Medicine Mount Sinai at Beth Israel New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zujun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medicine New York University Langone Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa Nguyen","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York University Langone Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stimson Pryor","family":"Schantz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York Eye and Ear Infirmary New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juskaran","family":"Chadha","sequence":"additional","affiliation":[{"name":"Department of Medicine Mount Sinai at Roosevelt Hospital New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis Benjamin","family":"Harrison","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Moffitt Comprehensive Cancer Center Tampa Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197206)29:6<1446::AID-CNCR2820290604>3.0.CO;2-C"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.102.1.132"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)02881-X"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/srao.2002.32435"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(99)00051-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01613-3"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21993"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01512-7"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.6199"},{"issue":"10","key":"e_1_2_6_11_1","first-page":"1747","article-title":"Comparison of fluorine\u201018\u2010fluorodeoxyglucose PET, MRI and endoscopy for staging head and neck squamous\u2010cell carcinomas","volume":"36","author":"Laubenbacher C","year":"1995","journal-title":"J Nucl Med."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199504000-00006"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200208000-00009"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13131470"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.01.004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.03.040"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23297"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2012.12.006"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(99)00179-6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.06.1975"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(80)90209-6"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2013.11.053"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.10.023"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2013.11.048"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2007.03.002"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(00)00063-4"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2007.06.005"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e3181ddd088"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.22929"},{"issue":"9","key":"e_1_2_6_30_1","first-page":"e322","article-title":"Patterns of relapse in squamous cell carcinoma of the tonsil \u2010 unilateral vs. bilateral radiation in the HPV\u2010era","volume":"7","author":"Ye A","year":"2015","journal-title":"Cureus."}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.24806","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.24806","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:11:53Z","timestamp":1696551113000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.24806"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,5]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1002\/hed.24806"],"URL":"https:\/\/doi.org\/10.1002\/hed.24806","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,5]]}}}