{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T16:02:45Z","timestamp":1781625765292,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,30]],"date-time":"2017-10-30T00:00:00Z","timestamp":1509321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to investigate whether adjuvant radiotherapy (RT) is efficacious for regional control and survival in patients with pN0 oral tongue cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinicopathological features of 166 patients with pN0 oral tongue cancer were compared between those who underwent adjuvant RT to the neck (neck RT\u2010positive) and those who did not (neck RT\u2010negative). Study endpoints were isolated regional recurrence and 3\u2010year regional recurrence\u2010free survival (RRFS). Propensity score matching was also performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cox regression analysis did not reveal any significant predictor of isolated regional recurrence, including RT field. Three\u2010year RRFS showed modest improvement in neck RT\u2010positive group compared to neck RT\u2010negative group before (92.2% vs 91.9%) and after propensity analysis (93.8% vs 83.3%), without statistical significance (log\u2010rank <jats:italic>P<\/jats:italic>\u2009=\u2009.85 and .37, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite more frequent unfavorable factors, the neck RT\u2010positive group had a comparable oncologic outcome to the neck RT\u2010negative group, suggesting that a marginal benefit in regional control might be expected from extending the RT field to the neck for pN0 oral tongue cancer.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.24980","type":"journal-article","created":{"date-parts":[[2017,10,30]],"date-time":"2017-10-30T14:02:57Z","timestamp":1509372177000},"page":"163-169","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy of postoperative neck irradiation for regional control in patients with pN0 oral tongue cancer: Propensity analysis"],"prefix":"10.1002","volume":"40","author":[{"given":"Yoon Kyoung","family":"So","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Inje University College of Medicine, Ilsan Paik Hospital Goyang\u2010Si Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongryul","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayeon","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010Hwan","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Chan","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1435-7786","authenticated-orcid":false,"given":"Man Ki","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2010 Head and Neck Surgery Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul 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