{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T10:00:14Z","timestamp":1784368814168,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,17]],"date-time":"2018-01-17T00:00:00Z","timestamp":1516147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sinonasal exophytic papillomas are rare. The multifocal form, florid papillomatosis, has not been yet described in literature. We report on the clinical features and the management of the different forms of exophytic papilloma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was conducted that included all patients with exophytic papilloma treated in our center over the past 12 years. We recorded clinical presentation, treatments, recurrences, pathology (p16 expression and human papillomavirus [HPV] status).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 13 patients with a mean follow\u2010up of 5 years. The main location of exophytic papilloma was the anterior part of the septum. Lesions were multifocal in 3 patients corresponding to florid papillomatosis. The main treatment was surgery. Cases of HPV\u201011 or HPV\u20106 were present in all forms of exophytic papilloma (dysplasia in 4 cases). Late recurrences occurred in 3 patients (2 patients with florid papillomatosis) over a period of 3 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Exophytic papilloma has 2 clinical presentations: localized and diffuse. Patients with florid papillomatosis should be monitored closely as recurrence seems to be frequent.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25042","type":"journal-article","created":{"date-parts":[[2018,1,17]],"date-time":"2018-01-17T05:09:44Z","timestamp":1516165784000},"page":"740-746","source":"Crossref","is-referenced-by-count":9,"title":["Exophytic sinonasal papillomas and nasal florid papillomatosis: A retrospective study"],"prefix":"10.1002","volume":"40","author":[{"given":"Romain","family":"Gl\u00e2tre","sequence":"first","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lo\u00efse","family":"De Kermadec","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issam Abd","family":"Alsamad","sequence":"additional","affiliation":[{"name":"Department of Pathology Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Badoual","sequence":"additional","affiliation":[{"name":"INSERM U970 Paris Cardiovascular Research Center (PARCC)  Paris France"},{"name":"Department of Pathology Universit\u00e9 Paris Descartes Sorbonne Paris\u2010Cit\u00e9 Paris France"},{"name":"H\u00f4pital Europ\u00e9en Georges Pompidou (HEGP) Assistance Publique H\u00f4pitaux de Paris (AP\u2010HP)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Gauthier","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Brugel","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Parra","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Coste","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"},{"name":"Universit\u00e9 Paris\u2010Est, Facult\u00e9 de M\u00e9decine Cr\u00e9teil France"},{"name":"INSERM U955 Cr\u00e9teil France"},{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery, H\u00f4pital Henri Mondor Assistance Publique H\u00f4pitaux de Paris (AP\u2010HP) Cr\u00e9teil France"},{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, Centre National de la Recherche Scientifique (CNRS) H\u00f4pital Intercommunal Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Pruli\u00e8re\u2010Escabasse","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"},{"name":"Universit\u00e9 Paris\u2010Est, Facult\u00e9 de M\u00e9decine Cr\u00e9teil France"},{"name":"INSERM U955 Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5193-5776","authenticated-orcid":false,"given":"Emilie","family":"Bequignon","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"},{"name":"Universit\u00e9 Paris\u2010Est, Facult\u00e9 de M\u00e9decine Cr\u00e9teil France"},{"name":"INSERM U955 Cr\u00e9teil France"},{"name":"Department of Oto\u2010Rhino\u2010Laryngology and Head and Neck Surgery, H\u00f4pital Henri Mondor Assistance Publique H\u00f4pitaux de Paris (AP\u2010HP) Cr\u00e9teil France"},{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, Centre National de la Recherche Scientifique (CNRS) H\u00f4pital Intercommunal Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3904"},{"issue":"1","key":"e_1_2_10_3_1","first-page":"31","article-title":"The papillomas of the sinonasal tract. 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