{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T22:03:33Z","timestamp":1764540213486,"version":"3.37.3"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hypocalcaemia is a common and serious complication after thyroidectomy. The purpose of this study is to assess the effectiveness of first postoperative day parathyroid hormone (PTH) measurement in order to predict the presence and severity of postthyroidectomy hypocalcaemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred consecutive cases undergoing total thyroidectomy in a tertiary referral center were prospectively assessed. Preoperative measurements of PTH were compared with postoperative levels in the first morning after surgery. All cases of hypocalcaemia were recorded and evaluated with regard to preoperative and postoperative levels of PTH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A decrease of 56% of PTH levels on the first postoperative day could accurately predict postoperative hypocalcaemia with a sensitivity and specificity of 80%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Serum PTH levels on the first postoperative day may be used as a reliable predictive marker for calcium supplementation need and even prolonged hospitalization in cases undergoing total thyroidectomy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25081","type":"journal-article","created":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T13:36:39Z","timestamp":1517492199000},"page":"1040-1045","source":"Crossref","is-referenced-by-count":20,"title":["Postoperative day 1 levels of parathyroid as predictor of occurrence and severity of hypocalcaemia after total thyroidectomy"],"prefix":"10.1002","volume":"40","author":[{"given":"Alexander D.","family":"Karatzanis","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despo P.","family":"Ierodiakonou","sequence":"additional","affiliation":[{"name":"Division of Social and Public Medicine University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel S.","family":"Fountakis","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stylianos G.","family":"Velegrakis","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery University of Erlangen Erlangen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9011-0315","authenticated-orcid":false,"given":"Maria V.","family":"Doulaptsi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel P.","family":"Prokopakis","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki N.","family":"Daraki","sequence":"additional","affiliation":[{"name":"Department of Endocrinology University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George A.","family":"Velegrakis","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology University of Crete Medical School Heraklion Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.212"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1808"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-012-0981-1"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7219"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200302000-00028"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9384"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.02.021"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814536848"},{"issue":"6","key":"e_1_2_5_10_1","first-page":"654","article-title":"Preoperative serum calcium levels as an indicator of postthyroidectomy hypocalcemia","volume":"39","author":"Amir A","year":"2010","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.127891"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-0057-2"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2014.06.003"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.008013"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-014-0042-6"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2012.03.011"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-012-1017-6"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-017-1586-5"},{"issue":"2","key":"e_1_2_5_19_1","first-page":"335","article-title":"Early postoperative parathyroid hormone level as a predictor of hypocalcaemia after total thyroidectomy","volume":"26","author":"Sharif SB","year":"2017","journal-title":"Mymensingh Med J"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815596341"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2014.07.006"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000181504.69230.87"},{"issue":"11","key":"e_1_2_5_23_1","first-page":"A5157","article-title":"Post\u2010operative parathyroid hormone can be used as a predictor of normocalcaemia after total thyroidectomy","volume":"62","author":"Abdel\u2010Halim CN","year":"2015","journal-title":"Dan Med J"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2007.06.036"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215113002600"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.09.004"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.892867"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2013.01.038"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2012.08.030"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1377-5"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6410"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599810395114"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2011.06.004"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e32834c4980"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.25081","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.25081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:59:01Z","timestamp":1695574741000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.25081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1002\/hed.25081"],"URL":"https:\/\/doi.org\/10.1002\/hed.25081","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"type":"print","value":"1043-3074"},{"type":"electronic","value":"1097-0347"}],"subject":[],"published":{"date-parts":[[2018,2]]}}}