{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:43:07Z","timestamp":1786977787984,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T00:00:00Z","timestamp":1542067200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 Cancer Center Support Grant (P30 CA008748)."],"award-info":[{"award-number":["P30 Cancer Center Support Grant (P30 CA008748)."]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We explored if age affects quality of life (QOL) in survivors of locally advanced human papillomavirus (HPV)\u2010related oropharyngeal squamous cell carcinoma (SCC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a cross\u2010sectional survey of 185 patients, at least 12 months from radiation, we evaluated generic (EuroQOL\u20105D questionnaire [EQ\u20105D]) and head and neck specific (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire\u2010Head and Neck 35\u2010questions [EORTC\u2010QLQ\u2010H&amp;N35]) QOL questionnaires and compared differences between younger (&lt;65) and older (\u226565) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age was 57.0 years (range 25\u201077 years), and 31 patients (16.8%) were \u226565 years old. There was no significant difference in EQ\u20105D global QOL scores by age (\n                      <jats:italic>P<\/jats:italic>\n                      = .53). Patients \u226565 years reported more immobility (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .01), problems with social eating (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .0001), and coughing (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .01). Patients \u226565 years were not more likely to ever require a gastrostomy (\n                      <jats:italic>P<\/jats:italic>\n                      = .24) but were more likely to remain gastrostomy\u2010dependent at the time of the survey (\n                      <jats:italic>P<\/jats:italic>\n                      = .02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite similar generic QOL, older survivors may have more mobility problems and issues with social eating compared with younger survivors deserving of further evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.25159","type":"journal-article","created":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T08:12:38Z","timestamp":1542096758000},"page":"2321-2328","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Long\u2010term quality of life in older patients with HPV\u2010related oropharyngeal cancer"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8411-0658","authenticated-orcid":false,"given":"Shrujal S.","family":"Baxi","sequence":"first","affiliation":[{"name":"Head and Neck Oncology Service, Department of Medicine Memorial Sloan Kettering Cancer Center  New York New York"},{"name":"Department of Medicine Weil Medical College of Cornell University  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Cullen","sequence":"additional","affiliation":[{"name":"Head and Neck Oncology Service, Department of 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