{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T23:00:52Z","timestamp":1778799652536,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T00:00:00Z","timestamp":1532563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The treatment failure for oral squamous cell carcinoma (SCC) frequently takes the form of local and regional recurrences. We investigated the role of lingual lymph nodes (LLNs) in the recurrence of SCC of the tongue and the floor of the mouth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 111 patients with SCC of the tongue and the floor of the mouth who received treatment between 2012 and 2017 were included in this study. The patients with lingual lymph nodes that were confirmed to be metastasis on pathological examination were classified into the LNN group. The demographic and clinical data differences between the No\u2010LLN group and the LLN group were compared. Statistical analyses were performed using the Pearson chi\u2010square test<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The total incidence of LLNs was 17.12% (19\/111) and 5 patients (4.5%) demonstrated LLN metastases. All the patients with LLN metastases had a neck lymph node status of N2 classification. The incidence and metastasis of the LLNs were associated with pathological classifications of SCC of the tongue and the floor of the mouth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LLNs are rare in patients with SCC of the tongue and the floor of the mouth, and they would be ready to be omitted. The dissection of these LLNs would be of benefit to those patients with advanced pathological grade.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25340","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T06:41:25Z","timestamp":1532673685000},"page":"2383-2388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Lingual lymph nodes in patients with squamous cell carcinoma of the tongue and the floor of the mouth"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2505-3403","authenticated-orcid":false,"given":"Jun","family":"Jia","sequence":"first","affiliation":[{"name":"State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei\u2010MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology Wuhan University Wuhan 430079 China"},{"name":"Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology Wuhan University Wuhan 430079 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng\u2010qi","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei\u2010MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology Wuhan University Wuhan 430079 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai\u2010xiao","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Stomatology Second Affiliated Hospital of Nanchang University Nanchang 330006 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.05.028"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-007-9088-3"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.09.071"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000161338.54515.b1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28686"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2010.12.009"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2007.12.002"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/61883763"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2009.10.001"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10259"},{"issue":"3","key":"e_1_2_8_12_1","first-page":"E67","article-title":"Metastasis to the lingual lymph node in patients with squamous cell carcinoma of the floor of the mouth: a report of two cases","volume":"55","author":"Umeda M","year":"2010","journal-title":"Kobe J Med Sci."},{"issue":"6","key":"e_1_2_8_13_1","first-page":"547","article-title":"Anatomic\u2010histologic study of the floor of the mouth: the lingual lymph nodes","volume":"45","author":"Ananian SG","year":"2015","journal-title":"Jpn J Clin Oncol."},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2012.02.014"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2002.0469"},{"issue":"6","key":"e_1_2_8_16_1","first-page":"350","article-title":"Discontinuous vs. in\u2010continuity neck dissection in carcinoma of the oral cavity. 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