{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T03:40:38Z","timestamp":1780544438285,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T00:00:00Z","timestamp":1544486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Oral tongue\/floor of mouth squamous cell carcinoma (OTFMSCC) with a depth of invasion (DOI)\u2009&gt;\u200910 mm involves extrinsic muscles and lingual neurovascular\/lymphatic bundles. \u201cCompartmental\u201d hemiglossopelvectomy (CHGP) was developed to improve loco\u2010regional control by \u201cen bloc\u201d removal of tumor and its pathways of spread.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective observational study on 45 CHGPs performed at a single institution for OTFMSCC with a DOI\u2009&gt;\u200910 mm at CT\/MR. Group A (<jats:italic>n<\/jats:italic>\u2009=\u200935) included na\u00efve patients, and group B (<jats:italic>n<\/jats:italic>\u2009=\u200910) recurrent cancers. We evaluated 2\u2010year overall survival (OS), disease\u2010free survival (DFS), local control (LC), and loco\u2010regional control (LRC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two\u2010year OS, DFS, LC, and LRC were 80%, 91%, 100%, and 94% for group A, and 27%, 26%, 67%, and 36% for group B, respectively. Salvage surgery and positive margins were significantly associated with worse prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CHGP is a reliable oncologic approach in primary surgery for advanced OTFMSCC. In recurrent cancers, survival remains poor.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25480","type":"journal-article","created":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T13:59:50Z","timestamp":1544536790000},"page":"110-115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Compartmental surgery for oral tongue and floor of the mouth cancer: Oncologic outcomes"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2391-9357","authenticated-orcid":false,"given":"Cesare","family":"Piazza","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Fondazione IRCCS, National Cancer Institute of Milan, University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Grammatica","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Brescia  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nausica","family":"Montalto","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Brescia  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Paderno","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Brescia  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Del Bon","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Brescia  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero","family":"Nicolai","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Brescia  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)90011-4"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199806183382503"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200204000-00005"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(01)00350-1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1758-3284-3-43"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2005.0029"},{"key":"e_1_2_8_8_1","volume-title":"International Union against Cancer. TNM Classification of Malignant Cancer","author":"Sobin LH","year":"2010"},{"key":"e_1_2_8_9_1","volume-title":"TNM Classification of Malignant Tumors","author":"Brierley JD","year":"2016"},{"key":"e_1_2_8_10_1","first-page":"259","article-title":"Compartmental surgery in tongue tumours: description of a new surgical technique","volume":"29","author":"Calabrese L","year":"2009","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_8_11_1","first-page":"201","article-title":"Observations on the morphology of the human tongue","volume":"73","author":"Abd El\u2010Malek S","year":"1938","journal-title":"J Anat"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-013-1076-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2013.06.003"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23001"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjom.1999.0031"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2009.10.011"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2010.12.006"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.1998.tb00260.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19940801)74:3<789::AID-CNCR2820740302>3.0.CO;2-A"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(00)00433-5"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980415)82:8<1443::AID-CNCR2>3.0.CO;2-A"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20309"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.25480","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.25480","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hed.25480","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.25480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T16:46:11Z","timestamp":1694709971000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.25480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,11]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1002\/hed.25480"],"URL":"https:\/\/doi.org\/10.1002\/hed.25480","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,11]]},"assertion":[{"value":"2017-07-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}