{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T05:40:28Z","timestamp":1771911628420,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T00:00:00Z","timestamp":1545004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2015A030313181"],"award-info":[{"award-number":["2015A030313181"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772890"],"award-info":[{"award-number":["81772890"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81672676"],"award-info":[{"award-number":["81672676"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81402251"],"award-info":[{"award-number":["81402251"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81472521"],"award-info":[{"award-number":["81472521"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Reconstruction of hemiglossectomy defects requires careful flap design to avoid adverse functional and aesthetic outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Hemitongue specimens were obtained from minipigs to study the three\u2010dimensional anatomy and to define anatomic landmarks for precise measurements of flap requirement. The concept developed in animal models was then applied to hemiglossectomy reconstruction in clinical practice. Sixty\u2010one patients were randomly enrolled into the following two groups: a \u201cfive\u2010point eight\u2010line segment\u201d (FIPELS) flap design group (28 patients) and a conventional group (33 patients). Functional and aesthetic outcomes were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All flaps designed with the FIPELS technique matched the hemiglossectomy defects without the need for flap trimming, thus reducing the operating time (<jats:italic>P<\/jats:italic>\u2009=\u2009.03). Swallowing functions, speech intelligibility, and aesthetic outcomes were superior in the FIPELS group than that in the conventional group (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The FIPELS flap design for hemiglossectomy reconstruction yields improved functional and aesthetic outcomes compared to a conventional flap design.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25571","type":"journal-article","created":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T13:16:30Z","timestamp":1545052590000},"page":"1359-1366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["\u201cFive\u2010point eight\u2010line\u201d anatomic flap design for precise hemitongue reconstruction"],"prefix":"10.1002","volume":"41","author":[{"given":"Song","family":"Fan","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Department of Surgery Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts"},{"name":"Oral &amp; Maxillofacial\u2010Head &amp; Neck Digital Precision Reconstruction Technology Research Center of Guangdong Province  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qun\u2010Xing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han\u2010Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao\u2010Jin","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Institute of Hearing and Speech\u2010Language Science Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Neurobiology Nanjing Medial University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You\u2010Yuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao\u2010Yu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Xiong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo\u2010Kai","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Ho\u2010Young","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Surgery Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lile","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery The Second Xiangya Hospital, Central South University  Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Sun","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital Cancer Center Harvard Medical School  Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing\u2010Hao","family":"Wu","sequence":"additional","affiliation":[{"name":"Cutaneous Biology Research Center Massachusetts General Hospital, Harvard Medical School  Charlestown Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peirong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery The University of Texas MD Anderson Cancer Center  Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9855-4391","authenticated-orcid":false,"given":"Jin\u2010Song","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Oral &amp; 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