{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:45:43Z","timestamp":1786977943145,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T00:00:00Z","timestamp":1547251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (\u226570\u2009years old, mean 76\u2009years) treated with TLM was made. A systematic review of the literature was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Six patients (8%) had postoperative complications, but no treatment\u2010related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five\u2010year disease\u2010specific survival (DSS), overall survival, and laryngectomy\u2010free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (&gt;85%) and DSS (&gt;90%) rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.25616","type":"journal-article","created":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T12:03:34Z","timestamp":1547294614000},"page":"1816-1823","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Transoral laser microsurgery for glottic cancer in the elderly: Efficacy and safety"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3063-0890","authenticated-orcid":false,"given":"Juan P.","family":"Rodrigo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Hospital Universitario Central de Asturias University of Oviedo, ISPA, IUOPA, CIBERONC  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Garc\u00eda\u2010Velasco","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Hospital Universitario Central de Asturias University of Oviedo, ISPA, IUOPA, CIBERONC  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Ambrosch","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Christian\u2010Albrechts\u2010University of Kiel  Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Vander Poorten","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology, Head and Neck Surgery University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Oncology, Section Head and Neck Oncology KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Su\u00e1rez","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Hospital Universitario Central de Asturias University of Oviedo, ISPA, IUOPA, CIBERONC  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1363-8559","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Coca\u2010Pelaz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Hospital Universitario Central de Asturias University of Oviedo, ISPA, IUOPA, CIBERONC  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0445-112X","authenticated-orcid":false,"given":"Primoz","family":"Strojan","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Institute of Oncology  Ljubljana Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3710-5706","authenticated-orcid":false,"given":"Kate","family":"Hutcheson","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Section of Speech Pathology and Audiology MD Anderson Cancer Center  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt J.","family":"Folz","sequence":"additional","affiliation":[{"name":"ENT Department Karl Hansen Clinic  Bad Lippspringe Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Bernal\u2010Sprekelsen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Rinaldo","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology\u2010Head and neck surgery, University of Udine School of Medicine  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl E.","family":"Silver","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Arizona College of Medicine  Phoenix Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8247-8002","authenticated-orcid":false,"given":"Alfio","family":"Ferlito","sequence":"additional","affiliation":[{"name":"International Head and Neck Scientific Group  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,12]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"World Health Organization. 10 facts on ageing and the life course.http:\/\/www.who.int\/features\/factfiles\/ageing\/en\/. 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