{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T07:05:49Z","timestamp":1789110349915,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T00:00:00Z","timestamp":1550102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Parotidectomy in melanoma of the coronal scalp and face with clinically involved cervical lymph node metastasis is based on predicted cervical lymphatic drainage described by O'Brien.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In total, 40 parotidectomies with en bloc therapeutic neck dissection were retrospectively analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Lymphatic spread of melanoma to the parotid lymph nodes was observed in 10 of 40 specimens (25%). Eight of the 10 parotid\u2010positive patients developed a recurrence vs 17 of the 30 parotid\u2010negative patients (<jats:italic>P<\/jats:italic>\u2009=\u20090.28). There were no differences in overall survival, melanoma\u2010specific survival, and disease\u2010free survival between the parotid\u2010positive and parotid\u2010negative patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although in this series no survival differences were found, parotidectomy still merits a sustained role in therapeutic neck dissection procedures to improve regional control and to prevent facial nerve damage after surgery for a second relapse from occult metastases in the parotid.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25670","type":"journal-article","created":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T16:23:24Z","timestamp":1550161404000},"page":"2264-2270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Parotidectomy in patients with head and neck cutaneous melanoma with cervical lymph node involvement"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6595-7749","authenticated-orcid":false,"given":"Danique M.S.","family":"Berger","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery and Oncology Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martinus M.","family":"van Veen","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Oncology Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max F.","family":"Madu","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.J.","family":"van Akkooi","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4992-8024","authenticated-orcid":false,"given":"Wouter V.","family":"Vogel","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"},{"name":"Department of Radiotherapy Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfons J.M.","family":"Balm","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Oncology Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"},{"name":"Department of Maxillofacial Surgery Academic Medical Center  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem M.C.","family":"Klop","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Oncology Netherlands Cancer Institute \u2013 Antoni van Leeuwenhoek  Amsterdam The Netherlands"},{"name":"Department of Maxillofacial Surgery Academic Medical Center  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880170311"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21865"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(99)80330-4"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.1112"},{"issue":"4","key":"e_1_2_6_6_1","first-page":"570","article-title":"Patterns of lymphatic drainage from the skin in patients with 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