{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:09:10Z","timestamp":1790636950017,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T00:00:00Z","timestamp":1551916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["HHSN261201800012I\/ HHSN26100001"],"award-info":[{"award-number":["HHSN261201800012I\/ HHSN26100001"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA 086862"],"award-info":[{"award-number":["P30 CA 086862"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Recent declines in cancer incidence and mortality have not been distributed equally across the United States. Factors such as tobacco cessation and human papillomavirus presence might differentially affect urban and rural portions of the country.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used the Surveillance, Epidemiology, and End Results database to assess cancer incidence rates and trends from 1973 to 2015. We compared incidence rates for oral cavity, oropharynx, and larynx cancer in urban and rural counties and identified trends using Joinpoint software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Incidence of larynx and oral cavity cancer are decreasing faster in urban areas than in rural areas, while incidence of oropharynx cancer is increasing faster in rural areas than urban areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Relative trends in incidence of larynx, oral cavity, and oropharynx cancer over the past 40\u2009years are unfavorable for rural United States counties compared with urban areas. Cancer control programs should take this into account.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25736","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T10:59:46Z","timestamp":1551956386000},"page":"2619-2624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Incidence trends for upper aerodigestive tract cancers in rural United States counties"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1829-7258","authenticated-orcid":false,"given":"Nitin A.","family":"Pagedar","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0041-1654","authenticated-orcid":false,"given":"Amanda R.","family":"Kahl","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kendall K.","family":"Tasche","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1680-1334","authenticated-orcid":false,"given":"Aaron T.","family":"Seaman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan J.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Psychology and Brain Sciences University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Bryant","family":"Howren","sequence":"additional","affiliation":[{"name":"Department of Psychology and Brain Sciences University of Iowa  Iowa City Iowa"},{"name":"VHA Office of Rural Health Resource Center Iowa City VA Healthcare System  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Charlton","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.94.10.1682"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss6601a1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-17-0430"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss6614a1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27042"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1382"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-0361.2008.00147.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2014.10.024"},{"key":"e_1_2_7_10_1","unstructured":"Surveillance Epidemiology and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence \u2010 SEER 9 Regs Research Data Nov 2017 Sub (1973\u20132015) <Katrina\/Rita Population Adjustment> \u2212 Linked To County Attributes \u2010 Total US 1969\u20132016 Counties National Cancer Institute DCCPS Surveillance Research Program released April 2018 based on the November2017submission."},{"key":"e_1_2_7_11_1","unstructured":"Joinpoint Regression Program Version 4.6.0.0 \u2010 April2018; Statistical Methodology and Applications Branch Surveillance Research Program National Cancer Institute."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z"},{"issue":"1","key":"e_1_2_7_13_1","first-page":"4","article-title":"Growth of the epidemic of human papillomavirus\u2010related oropharyngeal carcinomas in whites in selected US metropolitan and nonmetropolitan counties, 1992\u20102013","volume":"44","author":"Polednak AP","year":"2017","journal-title":"J Registry Manag"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6702a1"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2017.1307516"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090198117709318"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2018.01.016"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-017-4567-2"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.25736","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.25736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T14:37:57Z","timestamp":1694270277000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.25736"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,7]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1002\/hed.25736"],"URL":"https:\/\/doi.org\/10.1002\/hed.25736","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,7]]},"assertion":[{"value":"2018-11-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}