{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T18:36:36Z","timestamp":1770834996983,"version":"3.50.1"},"reference-count":77,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,3,23]],"date-time":"2019-03-23T00:00:00Z","timestamp":1553299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We aimed to investigate the prognostic role of examined (dissected) lymph nodes (ELNs), negative LNs (NLNs), and positive (metastatic) LNs (PLNs) counts and LN ratio (LNR\u2009=\u2009PLNs\/ELNs\u00d7100) in patients with major salivary gland cancer (SGC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were retrieved for major SGC patients diagnosed between 1988 and 2011 from Surveillance, Epidemiology, and End Results program.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We have included 5446 patients with major SGC. Most patients had parotid gland cancer (84.61%). Patients having &gt;18 ELNs, &gt;4 PLNs, and &gt;33.33% LNR were associated with a worse survival. Moreover, older age, male patients, grade IV, distant stage, unmarried patients, submandibular gland cancer, and received chemotherapy but not received surgery were significantly associated with a worse survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We demonstrated that patients with &gt;18 ELNs and &gt;4 PLNs counts, and &gt;33.33% LNR were high\u2010risk group patients. We strongly suggest adding the ELNs and PLNs counts and\/or LNR into the current staging system.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25742","type":"journal-article","created":{"date-parts":[[2019,3,24]],"date-time":"2019-03-24T02:59:17Z","timestamp":1553396357000},"page":"2625-2635","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer"],"prefix":"10.1002","volume":"41","author":[{"given":"Khaled Mosaad","family":"Elhusseiny","sequence":"first","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University  Cairo Egypt"},{"name":"Online Research Club (http:\/\/www.onlineresearchclub.org\/"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma Abd\u2010Elshahed","family":"Abd\u2010Elhay","sequence":"additional","affiliation":[{"name":"Online Research Club 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