{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T23:17:03Z","timestamp":1789168623490,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T00:00:00Z","timestamp":1558915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The recently described Milan system provides a unified way of categorizing salivary gland fine\u2010needle aspiration (FNA) cytology. We aim to use this system to stratify risk of malignancy in parotid FNAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective case series, 376 FNAs were preoperatively performed for 573 parotidectomies over 14\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Risk of malignancy on FNA is as follows: nondiagnostic 14.5%, non\u2010neoplastic 26.7%, atypia of undetermined significance 29.3%, benign neoplasm 2.7%, neoplasm of uncertain malignant potential 19.1%, suspicious for malignancy 87.5%, and malignant 100%. The specific diagnoses of pleomorphic adenoma and Warthin tumor on FNA have high positive predictive value of 97.5% and 96.6%, respectively. Multivariate regression associates smaller size of lesion with a nondiagnostic or indeterminate result. Seniority of operator is associated with a lower likelihood of a nondiagnostic result.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This large Asian series validates the Milan system as a valuable tool in stratifying malignancy risk of parotid FNAs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25804","type":"journal-article","created":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T11:34:41Z","timestamp":1558956881000},"page":"3125-3132","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Risk stratification of fine\u2010needle aspiration cytology of parotid neoplasms based on the Milan system\u2014Experience from a tertiary center in Asia"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5265-4191","authenticated-orcid":false,"given":"Kevin C. 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