{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:53:52Z","timestamp":1790726032376,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T00:00:00Z","timestamp":1563235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005689","name":"G\u00f6teborgs L\u00e4kares\u00e4llskap","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005689","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005009","name":"Stiftelsen Assar Gabrielssons Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to investigate how common temporomandibular disorder (TMD) symptoms are among head and neck cancer (HNC) patients before and after oncological treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010nine patients with HNC receiving radiotherapy were enrolled in the study. Patients were examined before radiotherapy and at 6 and 12\u2009months after radiotherapy to evaluate the function and tenderness of the temporomandibular jaw and the muscles of mastication as well as the patient\u2010reported symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6 months after radiotherapy, there was a large increase in the number of patients reporting problems with opening their mouth, fatigue, stiffness, and pain of the jaw. Sixty\u2010eight percent of the patients had symptoms of TMD before oncological treatment and 94% and 81% had symptoms at the 6\u2010 and 12\u2010month follow\u2010up, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The signs and symptoms of TMD escalate after radiotherapy, with symptoms peaking at 6 months after radiotherapy. Most commonly, patients suffer from restricted mouth opening, stiffness, fatigue, and pain of the jaw.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25878","type":"journal-article","created":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T06:44:28Z","timestamp":1563345868000},"page":"3570-3576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Temporomandibular disorder in head and neck cancer patients undergoing radiotherapy: Clinical findings and patient\u2010reported symptoms"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4058-2477","authenticated-orcid":false,"given":"Nina","family":"Pauli","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Mejersj\u00f6","sequence":"additional","affiliation":[{"name":"Clinic of Orofacial Pain Sahlgrenska Academy and Public Dental Health  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodil","family":"Fagerberg\u2010Mohlin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Finizia","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000181507.69620.14"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0347(200102)23:2<113::AID-HED1006>3.0.CO;2-W"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2012.744466"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2016.1143564"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2014.892209"},{"key":"e_1_2_7_7_1","volume-title":"Management of Temporomandibular Disorders and Occlusion","author":"Okeson JP","year":"2013"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1986.tb01540.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1990.0059"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.755"},{"issue":"1","key":"e_1_2_7_11_1","first-page":"1","article-title":"Clinical signs indicative of temporomandibular disorders in adults: time trends and associated factors","volume":"37","author":"Kohler AA","year":"2013","journal-title":"Swed Dent J"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.20.2441"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.02.013"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2013.837583"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2016.1223341"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2015.1037864"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20760"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70044-2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103-5150.029.002.AO15"}],"container-title":["Head &amp; 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