{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:35:52Z","timestamp":1775043352884,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T00:00:00Z","timestamp":1571961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Our goal was to elucidate the differences in degree of technical difficulty of thyroidectomy in patients with autoimmune thyroid diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Charts of adult patients who had undergone thyroidectomy were reviewed. Patients with Hashimoto's Thyroiditis (HT) or Graves' Disease (GD) were individually compared to a control group of patients with early stage malignancy or goiter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The HT (n = 65) group was significantly more likely to have friable (<jats:italic>P\u2009=<\/jats:italic> .001) and fibrotic (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) thyroids, longer operative times (<jats:italic>P<\/jats:italic> = .02), and a 22\u2010modifier (<jats:italic>P<\/jats:italic> = .005). The GD (n = 169) group was significantly more likely to have friable (<jats:italic>P\u2009&lt;<\/jats:italic> .001), vascular (<jats:italic>P\u2009&lt;<\/jats:italic> .001), fibrotic (<jats:italic>P\u2009=<\/jats:italic> .038), and heavy (<jats:italic>P<\/jats:italic> = .002) thyroids, longer operative times (<jats:italic>P<\/jats:italic> = .03), increased length of stay (<jats:italic>P<\/jats:italic> = .01) and a 22\u2010modifier (<jats:italic>P<\/jats:italic> = .01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our experience at an institution with a high\u2010volume thyroid practice demonstrates that patients with autoimmune thyroid disease have consistent qualitative changes of the thyroid and significantly increased operative times and surgical difficulty.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.25991","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T12:34:17Z","timestamp":1572006857000},"page":"262-268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Degree of technical difficulty of thyroidectomy for autoimmune thyroid disease"],"prefix":"10.1002","volume":"42","author":[{"given":"Robert","family":"Saadi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Pennsylvania State University, College of Medicine  Hershey Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Brandt","sequence":"additional","affiliation":[{"name":"College of Medicine The Pennsylvania State University  Hershey 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