{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:04:37Z","timestamp":1789646677614,"version":"4.0.0"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:00:00Z","timestamp":1581465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Radiation to the head and neck is a well\u2010established risk factor for the development of carotid artery stenosis. Our objective was to identify the prevalence, incidence, and degree of carotid stenosis in patients with a history of head and neck irradiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was performed according to the PRISMA guidelines. A random effects model meta\u2010analysis was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nineteen studies comprising 1479 patients were included. The prevalence of carotid stenosis &gt;50%, &gt;70%, and carotid occlusion was 25% (95% CI: 19%\u201032%), 12% (95% CI: 7%\u201017%), and 4% (95% CI: 2%\u20108%), respectively. The cumulative 12\u2010month incidence of carotid stenosis &gt;50% was 4% (95% CI: 2%\u20105%), the 24\u2010month was 12% (95% CI: 9%\u201015%), and the 36\u2010month was 21% (95% CI: 9%\u201036%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The yearly incidence of carotid stenosis &gt;50% increased every year during the first 3\u2009years following radiotherapy. We propose routine yearly Doppler ultrasound screening beginning 1 year after head and neck radiotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.26102","type":"journal-article","created":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T06:41:52Z","timestamp":1581489712000},"page":"1077-1088","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Prevalence of carotid stenosis following radiotherapy for head and neck cancer: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8715-6651","authenticated-orcid":false,"given":"Pavlos","family":"Texakalidis","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Emory University School of Medicine  Atlanta 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