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While prior studies have summarized histologic details, a clinically focused review is currently lacking in the literature. This review describes the presentation, histopathology, imaging, treatment, and prognosis of newly described or recently evolving sinonasal malignancies while highlighting the distinguishing features of these entities. It includes teratocarcinosarcoma, human papillomavirus\u2010related multiphenotypic carcinoma, biphenotypic sinonasal sarcoma, sinonasal renal cell\u2010like adenocarcinoma, NUT\u2010midline carcinoma, squamous cell carcinoma associated with inverted papilloma, sinonasal undifferentiated carcinoma, and INI\u20101\u2010deficient sinonasal carcinoma. By describing the diagnosis, treatment, and prognosis of these recently defined entities, this clinical review aims to help guide oncologists in the clinical management of these patients.<\/jats:p>","DOI":"10.1002\/hed.26150","type":"journal-article","created":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T13:21:18Z","timestamp":1585142478000},"page":"2202-2212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Clinical management of emerging sinonasal malignancies"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2570-1706","authenticated-orcid":false,"given":"Kevin J.","family":"Contrera","sequence":"first","affiliation":[{"name":"Head &amp; Neck Institute, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil M.","family":"Woody","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Taussig Cancer Institute, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mobeen","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Pathology Robert J. 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