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Patients without surgical treatment had a significantly worse 3\u2010year overall survival. Mohs microscopic surgery led to significantly less occurrence of regional recurrences compared to wide excision. An ulcerating lesion, high mitotic activity, and lymphovascular invasion were significant prognostic factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgical resection is the cornerstone in the therapy of EPC and represents the therapeutic modality that offers the best chance of disease\u2010free survival. 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